caa a22 4500 465794815 CHVBK 20180323112034.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF00146553 doi (NATIONALLICENCE)springer-10.1007/BF00146553 Electrooculographic and electroretinographic study in the chicken after dopamine and haloperidol [Elektronische Daten] [Norma Wioland, Gabrielle Rudolf, Nicole Bonaventure] The implication of dopamine in the modulation of the standing potential of the eye was tested in the chicken through an indirect electrooculographic method and direct current electroretinogram (ERG) recording after haloperidol, a mixed D1-D2 antagonist. The standing potential of the eye was reduced within 15 min after intravitreal injection of the antagonist (150 μg). This effect is rapidly reversed by an application of dopamine. The fast oscillation was preserved but the light peak was either strongly reduced or abolished. The dark trough showed an apparently normal time course. The intensity-voltage function was studied for the various ERG components. After haloperidol the b-wave and the c-wave were strongly reduced, whereas the a-wave was little affected. Together with previous data obtained with intraocular injections of dopamine, our data suggest the involvement of dopamine in the modulation of the standing potential. They also support the hypothesis that the light peak, which is generated by a photoreceptor-pigment epithelium interaction, is influenced by dopamine or by a related substance. The modulatory effect could also be due to a balance between several neurotransmitter systems. Kluwer Academic Publishers, 1990 Chicken nationallicence electrooculogram nationallicence electroretinogram nationallicence dopamine nationallicence haloperidol nationallicence standing potential nationallicence Wioland Norma D.N.B.C., Centre de Neurchimie du CNRS, Strasbourg, France aut Rudolf Gabrielle D.N.B.C., Centre de Neurchimie du CNRS, Strasbourg, France aut Bonaventure Nicole D.N.B.C., Centre de Neurchimie du CNRS, Strasbourg, France aut Documenta Ophthalmologica Kluwer Academic Publishers 75/2(1990-09-01), 175-180 0012-4486 75:2<175 1990 75 10633 https://doi.org/10.1007/BF00146553 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00146553 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wioland Norma D.N.B.C., Centre de Neurchimie du CNRS, Strasbourg, France aut NATIONALLICENCE 700 1- Rudolf Gabrielle D.N.B.C., Centre de Neurchimie du CNRS, Strasbourg, France aut NATIONALLICENCE 700 1- Bonaventure Nicole D.N.B.C., Centre de Neurchimie du CNRS, Strasbourg, France aut NATIONALLICENCE 773 0- Documenta Ophthalmologica Kluwer Academic Publishers 75/2(1990-09-01), 175-180 0012-4486 75:2<175 1990 75 10633 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer