caa a22 4500 465794890 CHVBK 20180323112035.0 cr unu---uuuuu 170327e19901101xx s 000 0 eng 10.1007/BF00140494 doi (NATIONALLICENCE)springer-10.1007/BF00140494 Fundamental differences between the nonlinearities of pattern and focal electroretinograms [Elektronische Daten] [Vaegan,, Erich Sutter] We directly compared nonlinear kernels of normal human pattern electroretinograms (PERGs) and corresponding localized flash ERGs (FERGs). The FERG was triphasic and resembled an adaptive process because it decayed slowly without changing shape over several kernel orders and interpulse intervals. The PERG was biphasic in the slice nearest the diagonal of the second-order kernel, similar to the FERG in slices farthur from this diagonal, and without power in higher-order kernels. The unique PERG features were short-term effects that immediately followed a contrast transition. The appearance-disappearance PERG had a triphasic first-order kernel and a biphasic second-order kernel. The latter was similar to, but half the size of, that for the contrast-reversal PERG. When the first off-diagonal slices of the two PERG second-order kernels were analyzed in detail, we found in both that the first positive peak was larger than the FERG at intermediate spatial frequencies. Both PERG peaks in the slice had a low contrast threshold and were linear with contrast. The three FERG peaks of the corresponding FERG slice had a higher threshold and were saturated with increasing contrast. These observations show that the PERG contains substantial pattern specific nonlinear components and cannot be dismissed as merely the nonlinear subcomponents of the corresponding FERG. Kluwer Academic Publishers, 1990 Contrast nationallicence luminance nationallicence pattern electroretinograms nationallicence focal electroretinograms nationallicence spatial tuning nationallicence nonlinear analysis nationallicence Vaegan, Department of Ophthalmology, E27, Save Sight and Eye Health Institute, Sydney University, 2006, Sydney, Australia aut Sutter Erich Smith Kettlewell Eye Research Foundation, 94115, San Francisco, CA, USA aut Documenta Ophthalmologica Kluwer Academic Publishers 76/1(1990-11-01), 13-25 0012-4486 76:1<13 1990 76 10633 https://doi.org/10.1007/BF00140494 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00140494 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vaegan Department of Ophthalmology, E27, Save Sight and Eye Health Institute, Sydney University, 2006, Sydney, Australia aut NATIONALLICENCE 700 1- Sutter Erich Smith Kettlewell Eye Research Foundation, 94115, San Francisco, CA, USA aut NATIONALLICENCE 773 0- Documenta Ophthalmologica Kluwer Academic Publishers 76/1(1990-11-01), 13-25 0012-4486 76:1<13 1990 76 10633 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer