caa a22 4500 465794998 CHVBK 20180323112035.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF00142683 doi (NATIONALLICENCE)springer-10.1007/BF00142683 Oxygen-induced retinopathy in the newborn rat: a scoring system for the evaluation of retinal vascular changes [Elektronische Daten] Scoring system for OIR in the rat [Benedetto Ricci, Domenico Lepore, Enrico Zonghi, Giuseppe Calogero] The authors describe a scoring system they have developed for evaluating damage produced in the retinal vascular network of the newborn rat by exposure to oxygen. India ink-injected retinal flat mounts are used. The scoring system provides for division of the retina into three concentric zones with the optic disk as a center point. Each retinal quadrant is then examined for the presence of the following lesions of progressive severity: vaso-obliteration of the capillary network, loss of the periarteriolar capillary-free zone, newly formed capillary tufts. When more than one type of lesion is present in a quadrant, only the most severe lesion is considered. The numerical score corresponding to that lesion is then multiplied by the factor corresponding to the concentric zone in which the lesion lies to give the quadrant score. The total retinal score is represented by the sum of the four quadrant scores. This type of system, if adopted by other investigators, can facilitate precise and systematic description of the results of different experimental protocols. Kluwer Academic Publishers, 1991 Oxygen-induced retinopathy nationallicence retinopathy of prematurity nationallicence oxygen nationallicence retinal vasculature nationallicence scoring system nationallicence OIR : oxygen-induced retinopathy nationallicence ROP : retinopathy of prematurity nationallicence Ricci Benedetto Department of Ophthalmology, Catholic University, Rome, Italy aut Lepore Domenico Department of Ophthalmology, Catholic University, Rome, Italy aut Zonghi Enrico Department of Ophthalmology, Catholic University, Rome, Italy aut Calogero Giuseppe Department of Ophthalmology, Catholic University, Rome, Italy aut Documenta Ophthalmologica Kluwer Academic Publishers 76/3(1990-09-01), 241-249 0012-4486 76:3<241 1990 76 10633 https://doi.org/10.1007/BF00142683 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00142683 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ricci Benedetto Department of Ophthalmology, Catholic University, Rome, Italy aut NATIONALLICENCE 700 1- Lepore Domenico Department of Ophthalmology, Catholic University, Rome, Italy aut NATIONALLICENCE 700 1- Zonghi Enrico Department of Ophthalmology, Catholic University, Rome, Italy aut NATIONALLICENCE 700 1- Calogero Giuseppe Department of Ophthalmology, Catholic University, Rome, Italy aut NATIONALLICENCE 773 0- Documenta Ophthalmologica Kluwer Academic Publishers 76/3(1990-09-01), 241-249 0012-4486 76:3<241 1990 76 10633 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer