caa a22 4500 465795013 CHVBK 20180323112035.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF00142682 doi (NATIONALLICENCE)springer-10.1007/BF00142682 A long term follow up of ocular siderosis: Quantitative assessment of the electroretinogram [Elektronische Daten] [Rina Schechner, Benjamin Miller, Eliezer Merksamer, Ido Perlman] Siderosis oculi is a severe sequel of retained, iron made, intraocular foreign body. Iron atoms or ions, dissolved from the foreign body, may diffuse to the retina and produce irreversible cellular damage. Therefore, early extraction of an iron foreign body is recommended. When the risks of surgical intervention outweigh the danger of siderosis, the patient is periodically examined in order to detect the initial signs of siderosis. The most commonly used test for quantitative and objective assessment of retinal function is the electroretinogram (ERG). We report here a long term ERG follow-up (about 8 years) of a patient suffering from a unilateral iron intraocular foreign body. The development of siderosis was detected by any of the ERG responses; cone-dominated, rod-dominated or mixed cone-rod responses. However, the degree of the assessed damage varied and strongly depended upon the flash intensity used to elicit the ERG response and upon the ERG wave chosen to assess retinal function. The relationship between the ERG b- and a-waves showed a profound deterioration reflecting a reduction in signal transmission from the photoreceptors to the inner nuclear layer. These findings suggested that iron toxicity produced more damage to the inner retina than to the outer retina. Kluwer Academic Publishers, 1991 Electroretinogram nationallicence siderosis nationallicence retina nationallicence Schechner Rina The Rappaport Family Institute for Research in the Medical Sciences and Faculty of Medicine, Technion-Israel Institute of Technology, P.O. Box 9649, 31096, Haifa, Israel aut Miller Benjamin Department of Ophthalmology, Rambam Medical Center, Haifa, Israel aut Merksamer Eliezer Department of Ophthalmology, Bnei Zion Medical Center, Haifa, Israel aut Perlman Ido The Rappaport Family Institute for Research in the Medical Sciences and Faculty of Medicine, Technion-Israel Institute of Technology, P.O. Box 9649, 31096, Haifa, Israel aut Documenta Ophthalmologica Kluwer Academic Publishers 76/3(1990-09-01), 231-240 0012-4486 76:3<231 1990 76 10633 https://doi.org/10.1007/BF00142682 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00142682 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Schechner Rina The Rappaport Family Institute for Research in the Medical Sciences and Faculty of Medicine, Technion-Israel Institute of Technology, P.O. Box 9649, 31096, Haifa, Israel aut NATIONALLICENCE 700 1- Miller Benjamin Department of Ophthalmology, Rambam Medical Center, Haifa, Israel aut NATIONALLICENCE 700 1- Merksamer Eliezer Department of Ophthalmology, Bnei Zion Medical Center, Haifa, Israel aut NATIONALLICENCE 700 1- Perlman Ido The Rappaport Family Institute for Research in the Medical Sciences and Faculty of Medicine, Technion-Israel Institute of Technology, P.O. Box 9649, 31096, Haifa, Israel aut NATIONALLICENCE 773 0- Documenta Ophthalmologica Kluwer Academic Publishers 76/3(1990-09-01), 231-240 0012-4486 76:3<231 1990 76 10633 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer