caa a22 4500 465795323 CHVBK 20180323112036.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF00678406 doi (NATIONALLICENCE)springer-10.1007/BF00678406 Molecular analysis of structural protein genes of the yamagata-1 strain of defective subacute sclerosing panencephalitis virus. II. Nucleotide sequence of a cDNA corresponding to the P plus M dicistronic mRNA [Elektronische Daten] [Yasuhiro Yoshikawa, Hiroshi Tsuruoka, Mineo Matsumoto, Takeshi Haga, Tatsuo Shioda, Hiroshi Shibuta, Takeshi Sato, Kazuya Yamanouchi] The nucleotide sequence of a cloned cDNA corresponding to the P+M dicistronic mRNA of a subacute sclerosing panencephalitis (SSPE) virus was determined and compared with data of measles virus (MV). The dicistronic mRNA of the SSPE virus consisted of the 3′ proximal 626 nucleotides of P mRNA, intercistronic trinucleotides, a full length of M mRNA, and 75 poly A nucleotides. The part encoding the P protein had a high homology to MV, except at the noncoding region. The terminating consensus sequence of the P gene and the intercistronic trinucleotides of the SSPE virus were CTAC(A)6 and CCT; in MV they are TTAT(A)6 and CTT, respectively. In the M gene, the starting consensus sequence was exactly the same as MV, but at the 5′ proximal end, one third of this gene was different: The first ATG codon of the MV M gene signaling opening of the reading frame was changed to ACG in the SSPE virus and one long open reading frame started from the third ATG codon. The stop codon (TAG) of the MV M gene was also changed to CAG in the SSPE virus. Thus, the deduced SSPE-virus M protein lacked 50 amino acids at the amino terminal and had 15 extra amino acids at the carboxyl end when compared with the MV M protein. Kluwer Academic Publishers, 1990 SSPE virus nationallicence measles virus nationallicence phosphoprotein gene nationallicence matrix protein gene nationallicence dicistronic mRNA nationallicence mutation nationallicence Yoshikawa Yasuhiro Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut Tsuruoka Hiroshi Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut Matsumoto Mineo Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut Haga Takeshi Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut Shioda Tatsuo Department of Virus Infection, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut Shibuta Hiroshi Department of Virus Infection, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut Sato Takeshi Department of Measles Virus, National Institute of Health of Japan, Tokyo, Japan aut Yamanouchi Kazuya Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut Virus Genes Kluwer Academic Publishers 4/2(1990-07-01), 151-161 0920-8569 4:2<151 1990 4 11262 https://doi.org/10.1007/BF00678406 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00678406 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yoshikawa Yasuhiro Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Tsuruoka Hiroshi Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Matsumoto Mineo Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Haga Takeshi Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Shioda Tatsuo Department of Virus Infection, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Shibuta Hiroshi Department of Virus Infection, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Sato Takeshi Department of Measles Virus, National Institute of Health of Japan, Tokyo, Japan aut NATIONALLICENCE 700 1- Yamanouchi Kazuya Laboratory Animal Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan aut NATIONALLICENCE 773 0- Virus Genes Kluwer Academic Publishers 4/2(1990-07-01), 151-161 0920-8569 4:2<151 1990 4 11262 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer