caa a22 4500 465795404 CHVBK 20180323112036.0 cr unu---uuuuu 170327e19900201xx s 000 0 eng 10.1007/BF00393184 doi (NATIONALLICENCE)springer-10.1007/BF00393184 Avian endogenous provirus (ev-3) env gene sequencing: Implication for pathogenic retrovirus origination [Elektronische Daten] [A. Tikhonenko, O. Lomovskaya] The avian endogenous env gene product blocks the surface receptor and, as a result, cells become immune to related exogenous retroviruses. On the other hand, the same sequence can be included in the pathogenic retrovirus genome, as shown by oligonucleotide mapping. However, since the complete env gene sequence was not known, the comparison of genomic nucleotide sequences was not possible. Therefore an avian endogenous provirus with an intact env gene was cloned from a chicken gene bank and the regions coding for the C terminus of the gp85 and gp37 proteins were sequenced. Comparison of this sequence with those of other retroviruses proved that one of the pathogenic viruses associated with osteopetrosis is a cross between avian endogenous virus and Rous sarcoma virus. Klumer Academic Publishers, 1990 endogenous retrovirus nationallicence RAV-O nationallicence NTRE-2 nationallicence env sequencing nationallicence Tikhonenko A. Laboratory of Oncovirus Immunology, Institute of Carcinogenesis, All-Union Cancer Research Center, USSR Academy of Medical Sciences, Moscow, USSR aut Lomovskaya O. Laboratory of Oncovirus Immunology, Institute of Carcinogenesis, All-Union Cancer Research Center, USSR Academy of Medical Sciences, Moscow, USSR aut Virus Genes Kluwer Academic Publishers 3/3(1990-02-01), 251-258 0920-8569 3:3<251 1990 3 11262 https://doi.org/10.1007/BF00393184 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00393184 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tikhonenko A. Laboratory of Oncovirus Immunology, Institute of Carcinogenesis, All-Union Cancer Research Center, USSR Academy of Medical Sciences, Moscow, USSR aut NATIONALLICENCE 700 1- Lomovskaya O. Laboratory of Oncovirus Immunology, Institute of Carcinogenesis, All-Union Cancer Research Center, USSR Academy of Medical Sciences, Moscow, USSR aut NATIONALLICENCE 773 0- Virus Genes Kluwer Academic Publishers 3/3(1990-02-01), 251-258 0920-8569 3:3<251 1990 3 11262 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer