caa a22 4500 465795471 CHVBK 20180323112036.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF00569039 doi (NATIONALLICENCE)springer-10.1007/BF00569039 Becker Yechiel Department of Molecular Virology, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel aut Computer predictions of antigenic domains in human immunodeficiency virus-1 envelope glycoprotein: Comparison with reported experimental data [Elektronische Daten] [Yechiel Becker] Computer analyses of amino acid sequences in the human immunodeficiency virus-1 (HIV-1) envelope glycoprotein revealed that antigenic domains in the viral protein can be predicted on the basis of the physical properties of amino acids in the polypeptide chain. Relatively high values of surface probability, flexibility, and hydrophilicity were used as markers for domains of putative antigenicity. Comparison of the computer-predicted antigenic domains in the HIV-1 envelope with those reported experimentally indicate that computer analyses are able to predict antigenic domains. This study shows the usefulness of computer programs for the prediction of the antigenic domains in the HIV-1 envelope protein. Kluwer Academic Publishers, 1990 antigenic domains nationallicence computer predictions nationallicence envelope glycoprotein nationallicence experimental analysis of antigenicity nationallicence HIV-1 nationallicence Virus Genes Kluwer Academic Publishers 3/4(1990-04-01), 323-341 0920-8569 3:4<323 1990 3 11262 https://doi.org/10.1007/BF00569039 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00569039 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Becker Yechiel Department of Molecular Virology, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel aut NATIONALLICENCE 773 0- Virus Genes Kluwer Academic Publishers 3/4(1990-04-01), 323-341 0920-8569 3:4<323 1990 3 11262 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer