caa a22 4500 465795706 CHVBK 20180323112037.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF02539697 doi (NATIONALLICENCE)springer-10.1007/BF02539697 Syntheses of 2-(N-2-hydroxyalkyl-N,N-dimethylammonio)ethyl hydrogen phosphates and their physicochemical and antimicrobial properties [Elektronische Daten] [Kazuyuki Tsubone, Noriko Uchida] A series of new phosphate type of amphoterics having a 2-hydroxyalkyl group as a hydrocarbon chain, 2-(N-2-hydroxyalkyl-N,N-dimethylammonio)ethyl hydrogen phosphates (alkyl[R]:dodecyl, tetradecyl, hexadecyl), was synthesized and their physicochemical properties—isoelectric point, critical micelle concentration (CMCs), occupied area/molecule at interface and the change of free energy of micellization—and antimicrobial properties were investigated in comparison with those of sodium 2-(N-alkyl-N-methylamino)ethyl hydrogen phosphates. It was found that the CMCs and the occupied areas were observed to decrease due to a phosphobetaine moiety and a 2-hydroxyethyl group. Solution properties of the binary system of SDS/2-(N-2-hydroxytetradecyl-N,N-dimethylammonio)ethyl hydrogen phosphate in aqueous solutions were studied in terms of surface tension and pH value. On the other hand, it was observed that the Minimum inhibitory concentration (MICs) of 2-(N-2-hydroxyhexadecyl-N,N-dimethylammonio)ethyl hydrogen phosphate against fungi were smaller than those of chlorhexidine digluconate. AOCS Press, 1990 Tsubone Kazuyuki Cosmetics Laboratory, Kanebo, Ltd., 5-3-28 Kotobukicho, 250, Odawaracity, Kanagawa, Japan aut Uchida Noriko Cosmetics Laboratory, Kanebo, Ltd., 5-3-28 Kotobukicho, 250, Odawaracity, Kanagawa, Japan aut Journal of the American Oil Chemists' Society Springer-Verlag 67/6(1990-06-01), 394-399 0003-021X 67:6<394 1990 67 11746 https://doi.org/10.1007/BF02539697 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02539697 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tsubone Kazuyuki Cosmetics Laboratory, Kanebo, Ltd., 5-3-28 Kotobukicho, 250, Odawaracity, Kanagawa, Japan aut NATIONALLICENCE 700 1- Uchida Noriko Cosmetics Laboratory, Kanebo, Ltd., 5-3-28 Kotobukicho, 250, Odawaracity, Kanagawa, Japan aut NATIONALLICENCE 773 0- Journal of the American Oil Chemists' Society Springer-Verlag 67/6(1990-06-01), 394-399 0003-021X 67:6<394 1990 67 11746 Metadata rights reserved Springer special CC-BY-NC licence nationallicence SWISSBIB 465795706 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer