caa a22 4500 46580375X CHVBK 20180323112058.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF03348569 doi (NATIONALLICENCE)springer-10.1007/BF03348569 Total digoxin-like immunoreactive factor(s) in healthy population, uncomplicated term pregnancies and neonates [Elektronische Daten] [N. Krivoy, P. Jakobi, E. Paldi, G. Alroy] Free digoxin-like immunoreactive factors) (DLIF) which may have a homeostatic role, as documented in different physiological conditions, but is generally undetectable in plasma from normal population. Total digoxin-like immunoreactive factor(s) (protein bound and free) can be estimated after plasma is heated. In this study, total digoxin-like immunoreactive factor(s) as measured in plasma in a well defined control population and compared to healthy term pregnant women and neonates, categories known to be associated with increased free digoxin-like. immunoreactive factors) concentrations. The mean level of this factors) in the control group was 706 ± 129 pg digoxin equivalent/ml (pg/ml) and was unaffected by age and sex. Significantly increased levels of total digoxin-like immunoreactive factor(s) were found in pregnant women and neonates (928 ± 127 and 1242 ± 367 pg/ml, respectively). We conclude that levels of total digoxin-like immunoreactive factor(s) are increased in term pregnancies and neonates, similarly to its free form. However total digoxin-like immunoreactive factor(s) is detected in the normal population as a plasma component, contrary to its free form, which is generally undetectable. Italian Society of Endocrinology (SIE), 1990 Digoxin-like immunoreactive factor(s) nationallicence Krivoy N. Department of Medicine A and Clinical Pharmacology Unit, and Gynecology/Obstetrics B, Rambam Medical Center and Faculty of Medicine, Technion, Haifa, Israel aut Jakobi P. aut Paldi E. aut Alroy G. Department of Medicine A and Clinical Pharmacology Unit, and Gynecology/Obstetrics B, Rambam Medical Center and Faculty of Medicine, Technion, Haifa, Israel aut Journal of Endocrinological Investigation Springer International Publishing 13/1(1990-01-01), 9-12 0391-4097 13:1<9 1990 13 40618 https://doi.org/10.1007/BF03348569 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03348569 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Krivoy N. Department of Medicine A and Clinical Pharmacology Unit, and Gynecology/Obstetrics B, Rambam Medical Center and Faculty of Medicine, Technion, Haifa, Israel aut NATIONALLICENCE 700 1- Jakobi P. aut NATIONALLICENCE 700 1- Paldi E. aut NATIONALLICENCE 700 1- Alroy G. Department of Medicine A and Clinical Pharmacology Unit, and Gynecology/Obstetrics B, Rambam Medical Center and Faculty of Medicine, Technion, Haifa, Israel aut NATIONALLICENCE 773 0- Journal of Endocrinological Investigation Springer International Publishing 13/1(1990-01-01), 9-12 0391-4097 13:1<9 1990 13 40618 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer