caa a22 4500 465804225 CHVBK 20180323112059.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF03348638 doi (NATIONALLICENCE)springer-10.1007/BF03348638 Lack of expression of antigens for islet cell antibodies in rat fetal pancreas [Elektronische Daten] [Yuki Yamashiro, H. Taniguchi, S. Baba, T. Taniguchi, S. Kodama, S. Aono, G. Isshiki, T. Jinnouchi] It is not clear yet when pancreatic islet cells begin to express antigens for islet cell antibodies (ICA). Therefore, we studied whether human ICA-positive sera, crossreacting with adult rat islet cells, react with fetal and neonatal rat islet cells immunohistologically. The ICA did not react with fetal islet cells. On the other hand, neonatal islet cells over 2-3 weeks of age expressed the reactivities almost similar to those of the adult. It was suspected that pancreatic islet cells started to express their antigens to induce ICA gradually after birth. Italian Society of Endocrinology (SIE), 1990 Islet cell antibody nationallicence islet cell antigen nationallicence expression of antigenicity nationallicence fetus nationallicence neonate nationallicence rat nationallicence Yamashiro Yuki Second Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan aut Taniguchi H. Second Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan aut Baba S. Second Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan aut Taniguchi T. Department of Surgery, Nagahama Red Cross Hospital, Shiga, Japan aut Kodama S. Department of Pediatrics, Himeji Red Cross Hospital, Himeji, Japan aut Aono S. Department of Pediatrics, Osaka City University Medical School, Osaka, Japan aut Isshiki G. Department of Pediatrics, Osaka City University Medical School, Osaka, Japan aut Jinnouchi T. Jinnouchi Hospital, Kumamoto, Japan aut Journal of Endocrinological Investigation Springer International Publishing 13/7(1990-07-01), 601-603 0391-4097 13:7<601 1990 13 40618 https://doi.org/10.1007/BF03348638 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03348638 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yamashiro Yuki Second Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan aut NATIONALLICENCE 700 1- Taniguchi H. Second Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan aut NATIONALLICENCE 700 1- Baba S. Second Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan aut NATIONALLICENCE 700 1- Taniguchi T. Department of Surgery, Nagahama Red Cross Hospital, Shiga, Japan aut NATIONALLICENCE 700 1- Kodama S. Department of Pediatrics, Himeji Red Cross Hospital, Himeji, Japan aut NATIONALLICENCE 700 1- Aono S. Department of Pediatrics, Osaka City University Medical School, Osaka, Japan aut NATIONALLICENCE 700 1- Isshiki G. Department of Pediatrics, Osaka City University Medical School, Osaka, Japan aut NATIONALLICENCE 700 1- Jinnouchi T. Jinnouchi Hospital, Kumamoto, Japan aut NATIONALLICENCE 773 0- Journal of Endocrinological Investigation Springer International Publishing 13/7(1990-07-01), 601-603 0391-4097 13:7<601 1990 13 40618 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer