caa a22 4500 465804268 CHVBK 20180323112059.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF03348628 doi (NATIONALLICENCE)springer-10.1007/BF03348628 Chronobiology of catecholamine excretion in normal and diabetic men [Elektronische Daten] [G. Del Rio, C. Carani, A. Baldini, P. Marrama, L. Della Casa] The adrenomedullary response to stimuli is often elevated in poorly controlled insulin dependent diabetic patients, and it is controversial whether the adrenomedullary hyperactivity induces the suppression of the circadian rhythm of catecholamines. We have studied the urinary excretion of catecholamines in 11 diabetic patients during 48 h in 4-h collections. Eleven age and weight matched normal subjects served as controls. A circadian rhythm was detected for adrenaline and noradrenaline excretion both in normal and diabetic subjects, with the highest value for both catecholamines in the early afternoon. The mean daily adrenaline levels were significantly higher in diabetic than in control subjects (p < 0.05). The dopamine excretion was correlated with noradrenaline excretion in normal subjects but did not show a definite circadian rhythm. We conclude that the adrenomedullary hyperactivity does not affect the rhythmic fluctuations of adrenaline and noradrenaline. The dopamine excretion does not show circadian variations and this probably reflects the absence of a single controlling oscillator. Italian Society of Endocrinology (SIE), 1990 Catecholamines nationallicence IDDM nationallicence chronobiology nationallicence Del Rio G. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut Carani C. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut Baldini A. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut Marrama P. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut Della Casa L. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut Journal of Endocrinological Investigation Springer International Publishing 13/7(1990-07-01), 575-580 0391-4097 13:7<575 1990 13 40618 https://doi.org/10.1007/BF03348628 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03348628 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Del Rio G. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut NATIONALLICENCE 700 1- Carani C. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut NATIONALLICENCE 700 1- Baldini A. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut NATIONALLICENCE 700 1- Marrama P. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut NATIONALLICENCE 700 1- Della Casa L. Dipartimento di Endocrinologia e Metabolismo, Università di Modena, Istituto Patologia Medica, Via del Pozzo 71, 41100, Modena, Italy aut NATIONALLICENCE 773 0- Journal of Endocrinological Investigation Springer International Publishing 13/7(1990-07-01), 575-580 0391-4097 13:7<575 1990 13 40618 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer