caa a22 4500 465804519 CHVBK 20180323112100.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF03349551 doi (NATIONALLICENCE)springer-10.1007/BF03349551 Hyperprolactinemia and temporal lobe epilepsy in a woman: concomitant and persistent prolactin suppression and temporal lobe epilepsy relief [Elektronische Daten] [A. Gattereau, J. Vézina, S. Rousseau, P. Bielmann] It has been reported that hyperprolactinemia may be associated with increased temporal lobe activity. Coexisting hyperprolactinemia (97.5 ± 3.2 ng/ml) related to a pituitary tumefaction (8 mm) and Temporal Lobe Epilepsy (TLE), were observed in a 37-year-old woman. Carbamazepin (CBZ) therapy induced a marked improvement in TLE symptoms and EEG recordings, but did not influence hyperprolactinemia and related symptoms. Long-lasting (27 months) normoprolactinemia (19.4 ± 0.6 ng/ml) and TLE relief were achieved on a dopamine (DA) agonist medication, e.g. pergolide mesylate, 25-50 μg/day given over 8 months, and persisted as long as 27 months after drug withdrawal. Posttreatment CT scans showed progressive shrinkage of the pituitary tumor (2 mm) associated with an empty-sella. It is proposed that, whenever TLE and hyperprolactinemia coexist, therapy with a DA agonist such as pergolide mesylate, resulting in normoprolactinemia, may be beneficial in TLE control. Italian Society of Endocrinology (SIE), 1990 Prolactinoma nationallicence hyperprolactinoma nationallicence TLE nationallicence pergolide mesylate nationallicence Gattereau A. Sections of Endocrinology, Neuro-Radiology and Gynaecology, Hôpital Hôtel-Dieu and Université de Montréal, 3840 St-Urbain, H2W 1T8, Montréal, Québec, Canada aut Vézina J. Sections of Endocrinology, Neuro-Radiology and Gynaecology, Hôpital Hôtel-Dieu and Université de Montréal, 3840 St-Urbain, H2W 1T8, Montréal, Québec, Canada aut Rousseau S. Sections of Endocrinology, Neuro-Radiology and Gynaecology, Hôpital Hôtel-Dieu and Université de Montréal, 3840 St-Urbain, H2W 1T8, Montréal, Québec, Canada aut Bielmann P. Sections of Endocrinology, Neuro-Radiology and Gynaecology, Hôpital Hôtel-Dieu and Université de Montréal, 3840 St-Urbain, H2W 1T8, Montréal, Québec, Canada aut Journal of Endocrinological Investigation Springer International Publishing 13/3(1990-03-01), 247-249 0391-4097 13:3<247 1990 13 40618 https://doi.org/10.1007/BF03349551 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03349551 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gattereau A. Sections of Endocrinology, Neuro-Radiology and Gynaecology, Hôpital Hôtel-Dieu and Université de Montréal, 3840 St-Urbain, H2W 1T8, Montréal, Québec, Canada aut NATIONALLICENCE 700 1- Vézina J. Sections of Endocrinology, Neuro-Radiology and Gynaecology, Hôpital Hôtel-Dieu and Université de Montréal, 3840 St-Urbain, H2W 1T8, Montréal, Québec, Canada aut NATIONALLICENCE 700 1- Rousseau S. Sections of Endocrinology, Neuro-Radiology and Gynaecology, Hôpital Hôtel-Dieu and Université de Montréal, 3840 St-Urbain, H2W 1T8, Montréal, Québec, Canada aut NATIONALLICENCE 700 1- Bielmann P. Sections of Endocrinology, Neuro-Radiology and Gynaecology, Hôpital Hôtel-Dieu and Université de Montréal, 3840 St-Urbain, H2W 1T8, Montréal, Québec, Canada aut NATIONALLICENCE 773 0- Journal of Endocrinological Investigation Springer International Publishing 13/3(1990-03-01), 247-249 0391-4097 13:3<247 1990 13 40618 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer