caa a22 4500 465804802 CHVBK 20180323112101.0 cr unu---uuuuu 170327e19901101xx s 000 0 eng 10.1007/BF03349633 doi (NATIONALLICENCE)springer-10.1007/BF03349633 Growth hormone therapy in a poorly growing child with hypophosphatemic rickets [Elektronische Daten] [R. Lanes, H. Harrison] We treated a 10 6/12 year old prepubertal male with hypophosphatemic rickets, who was growing poorly despite appropriate treatment with calcitriol and phosphate, with exogenous growth hormone (for an initial trial period of 4 months, followed by 14 months of continuous treatment at a dose of 4 IU three times weekly) even though his growth hormone testing proved to be normal. His growth rate increased significantly during treatment with synthetic growth hormone (from a basal rate of 3.9 cm/yr to 9 cm/yr during the first 4 months of therapy and from 2.7 cm/yr to 6.0 cm/yr during next 14 months of treatment) and his predicted adult height increased as well. Slight metabolic changes were detected in this patient during treatment, with an increase in serum phosphorus and a decrease in twenty-four hour urine calcium concentrations. It would seem reasonable to evaluate the growth hormone status of children with hypophosphatemic rickets who are growing poorly despite appropriate therapy with calcitriol and phosphate and to consider a trial period of therapy with growth hormone in some of them. Italian Society of Endocrinology (SIE), 1990 Growth hormone nationallicence hypophosphatemic rickets nationallicence growth velocity nationallicence Lanes R. Department of Pediatrics, Hospital de Clínicas Caracas, Caracas, Venezuela aut Harrison H. Department of Pediatrics, Hospital de Clínicas Caracas, Caracas, Venezuela aut Journal of Endocrinological Investigation Springer International Publishing 13/10(1990-11-01), 833-837 0391-4097 13:10<833 1990 13 40618 https://doi.org/10.1007/BF03349633 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03349633 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lanes R. Department of Pediatrics, Hospital de Clínicas Caracas, Caracas, Venezuela aut NATIONALLICENCE 700 1- Harrison H. Department of Pediatrics, Hospital de Clínicas Caracas, Caracas, Venezuela aut NATIONALLICENCE 773 0- Journal of Endocrinological Investigation Springer International Publishing 13/10(1990-11-01), 833-837 0391-4097 13:10<833 1990 13 40618 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer