caa a22 4500 465804969 CHVBK 20180323112101.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF03349573 doi (NATIONALLICENCE)springer-10.1007/BF03349573 Severe hyperthyroidism due to metastatic papillary thyroid carcinoma with favorable outcome [Elektronische Daten] [M. Girelli, D. Casara, D. Rubello, M. Pelizzo, B. Busnardo, D. Ziliotto] A case of extremely severe hyperthyroidism due to bone metastasis of papillary thyroid cancer is described. Hyperthyroidism began in this patient soon after the discovery of pelvic metastasis and worsened after total thyroidectomy and after the first dose of radioiodine. The administration of methimazole, prednisone and multiple, fractioned and small doses of radioiodine cured the hyperthyroidism and stabilized the neoplastic growth. Hyperthyroidism lasted for at least six months and hypothyroidism appeared only after seven months. Thus, the fractionation of the doses of radioiodine together with antithyroid drugs appears to be an effective treatment in patients with hyperthyroidism due to metastatic thyroid cancer. Italian Society of Endocrinology (SIE), 1990 Metastatic thyroid cancer nationallicence hyperthyroidism nationallicence Girelli M. lstituto di Semeiotica Medica, Università di Padova, Via Ospedale 105, 35100, Padova, Italy aut Casara D. Divisione di Radioterapia e Medicina Nucleare, Ospedale di Padova, 35100, Padova, Italy aut Rubello D. lstituto di Semeiotica Medica, Università di Padova, Via Ospedale 105, 35100, Padova, Italy aut Pelizzo M. lstituto di Patologia Chirurgica II, Università di Padova, 35100, Padova, Italy aut Busnardo B. lstituto di Semeiotica Medica, Università di Padova, Via Ospedale 105, 35100, Padova, Italy aut Ziliotto D. lstituto di Semeiotica Medica, Università di Padova, Via Ospedale 105, 35100, Padova, Italy aut Journal of Endocrinological Investigation Springer International Publishing 13/4(1990-04-01), 333-337 0391-4097 13:4<333 1990 13 40618 https://doi.org/10.1007/BF03349573 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03349573 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Girelli M. lstituto di Semeiotica Medica, Università di Padova, Via Ospedale 105, 35100, Padova, Italy aut NATIONALLICENCE 700 1- Casara D. Divisione di Radioterapia e Medicina Nucleare, Ospedale di Padova, 35100, Padova, Italy aut NATIONALLICENCE 700 1- Rubello D. lstituto di Semeiotica Medica, Università di Padova, Via Ospedale 105, 35100, Padova, Italy aut NATIONALLICENCE 700 1- Pelizzo M. lstituto di Patologia Chirurgica II, Università di Padova, 35100, Padova, Italy aut NATIONALLICENCE 700 1- Busnardo B. lstituto di Semeiotica Medica, Università di Padova, Via Ospedale 105, 35100, Padova, Italy aut NATIONALLICENCE 700 1- Ziliotto D. lstituto di Semeiotica Medica, Università di Padova, Via Ospedale 105, 35100, Padova, Italy aut NATIONALLICENCE 773 0- Journal of Endocrinological Investigation Springer International Publishing 13/4(1990-04-01), 333-337 0391-4097 13:4<333 1990 13 40618 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer