caa a22 4500 465805183 CHVBK 20180323112102.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF03349587 doi (NATIONALLICENCE)springer-10.1007/BF03349587 Thyrotropin-releasing hormone increases plasma atrial natriuretic peptide levels in human [Elektronische Daten] [O. Sergev, K. Rácz, I. Varga, R. Kiss, L. Fütö, K. Mohari, Edit Gláz] The effect of thyrotropin-releasing hormone (TRH) on plasma atrial natriuretic peptide (ANP), TSH, prolactin, cortisol and aldosterone levels in 26 patients with normal pituitary and thyroid gland function was examined. Bolus iv injection of 200 μg TRH produced, between 0 and 60 min, a significant gradual rise of plasma ANP concentrations from 30.4 ± 2.3 to 54.8 ± 6.4 pg/ml (mean ± SE). Plasma prolactin and TSH concentrations increased four- and six-fold of basal values with peak responses at 15 and 30 min, respectively, whereas plasma cortisol and aldosterone concentrations remained unchanged after the drug treatment. The patients had no significant changes in blood pressure or pulse rate. We conclude that there may be indirect mechanism(s) which result in increased ANP levels after TRH administration. Italian Society of Endocrinology (SIE), 1990 Thyrotropin-releasing hormone nationallicence atrial natriuretic peptide nationallicence Sergev O. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut Rácz K. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut Varga I. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut Kiss R. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut Fütö L. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut Mohari K. FJC National Research Institute of Radiology and Radiohygiene, Budapest, Hungary aut Gláz Edit Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut Journal of Endocrinological Investigation Springer International Publishing 13/8(1990-09-01), 649-652 0391-4097 13:8<649 1990 13 40618 https://doi.org/10.1007/BF03349587 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03349587 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sergev O. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut NATIONALLICENCE 700 1- Rácz K. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut NATIONALLICENCE 700 1- Varga I. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut NATIONALLICENCE 700 1- Kiss R. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut NATIONALLICENCE 700 1- Fütö L. Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut NATIONALLICENCE 700 1- Mohari K. FJC National Research Institute of Radiology and Radiohygiene, Budapest, Hungary aut NATIONALLICENCE 700 1- Gláz Edit Second Department of Medicine, Semmelweis University School of Medicine, Szentkirályi u. 46, H-1088, Budapest, Hungary aut NATIONALLICENCE 773 0- Journal of Endocrinological Investigation Springer International Publishing 13/8(1990-09-01), 649-652 0391-4097 13:8<649 1990 13 40618 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer