caa a22 4500 465805205 CHVBK 20180323112102.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF03349592 doi (NATIONALLICENCE)springer-10.1007/BF03349592 Acromegaly, multinodular goiter and silent polyostotic fibrous dysplasia, A variant of the McCune — Albright syndrome [Elektronische Daten] [R. Abs, A. Beckers, F. Van de Vyver, A. De Schepper, A. Stevenaert, G. Hennen] A 36-year-old woman is reported with a possible variant of the McCune-Albright syndrome. The triad was incomplete because of the absence of skin pigmentation and since the sexual precocity was not evident. The presence of a pituitary mass and the secretory dynamics of growth hormone and prolactin were suggestive of a mam-mosomatotroph cell adenoma. A toxic multinodular goiter was also associated, but unique was the spontaneous normalization of the thyroid function. Unusual was the silent evolution of the polyostotic fibrous dysplasia, which was only fortuitously discovered during magnetic resonance imaging of the pituitary region. Treatment of the acromegaly with the long-acting somatostatin analogue octreotide resulted in an important inhibition of the GH secretion and in a reduction of the volume of the pituitary adenoma. Italian Society of Endocrinology (SIE), 1990 Fibrous dysplasia (polyostotic) nationallicence acromegaly nationallicence hyperthyroidism nationallicence goiter nationallicence octreotide nationallicence Abs R. Department of Endocrinology, University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium aut Beckers A. Department of Endocrinology, University of Liège, B-4000, Sart-Tilman, Belgium aut Van de Vyver F. Research Group for Biomedical NMR, University of Antwerp, B-2610, Wilrijk, Belgium aut De Schepper A. Department of Radiology, University of Antwerp, B-2610, Wilrijk, Belgium aut Stevenaert A. Department of Neurosurgery, University of Liège, B-4000, Sart-Tilman, Belgium aut Hennen G. Department of Endocrinology, University of Liège, B-4000, Sart-Tilman, Belgium aut Journal of Endocrinological Investigation Springer International Publishing 13/8(1990-09-01), 671-675 0391-4097 13:8<671 1990 13 40618 https://doi.org/10.1007/BF03349592 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03349592 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Abs R. Department of Endocrinology, University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium aut NATIONALLICENCE 700 1- Beckers A. Department of Endocrinology, University of Liège, B-4000, Sart-Tilman, Belgium aut NATIONALLICENCE 700 1- Van de Vyver F. Research Group for Biomedical NMR, University of Antwerp, B-2610, Wilrijk, Belgium aut NATIONALLICENCE 700 1- De Schepper A. Department of Radiology, University of Antwerp, B-2610, Wilrijk, Belgium aut NATIONALLICENCE 700 1- Stevenaert A. Department of Neurosurgery, University of Liège, B-4000, Sart-Tilman, Belgium aut NATIONALLICENCE 700 1- Hennen G. Department of Endocrinology, University of Liège, B-4000, Sart-Tilman, Belgium aut NATIONALLICENCE 773 0- Journal of Endocrinological Investigation Springer International Publishing 13/8(1990-09-01), 671-675 0391-4097 13:8<671 1990 13 40618 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer