caa a22 4500 465808050 CHVBK 20180323112108.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00943890 doi (NATIONALLICENCE)springer-10.1007/BF00943890 Solvation effects in human serum albumin radiolysis in the presence of dimethyl sulfoxide [Elektronische Daten] [V. Pogorelyi, V. Barvinchenko, V. Turov] PMR and electrophoresis have been applied to examine hydration changes in protein molecules due to the presence of the electron donor dimethylsulfoxide DMSO, which influences the radiolysis of human serum albumin HSA. The reactions of aqueous HSA with added DMSO show that the DMSO on the one hand acts as a protector, which prevents the formation of low-molecular protein forms on reaction with hydroxyl radicals, and on the other alters the protein hydration, which facilitates thiol-di-sulfide exchange, which leads to oligomers. Plenum Publishing Corporation, 1990 Pogorelyi V. Pisarzhevskii Physical Chemistry Institute, Ukrainian Academy of Sciences, Kiev aut Barvinchenko V. Pisarzhevskii Physical Chemistry Institute, Ukrainian Academy of Sciences, Kiev aut Turov V. Pisarzhevskii Physical Chemistry Institute, Ukrainian Academy of Sciences, Kiev aut Theoretical and Experimental Chemistry Kluwer Academic Publishers-Plenum Publishers 26/1(1990-01-01), 98-101 0040-5760 26:1<98 1990 26 11237 https://doi.org/10.1007/BF00943890 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00943890 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pogorelyi V. Pisarzhevskii Physical Chemistry Institute, Ukrainian Academy of Sciences, Kiev aut NATIONALLICENCE 700 1- Barvinchenko V. Pisarzhevskii Physical Chemistry Institute, Ukrainian Academy of Sciences, Kiev aut NATIONALLICENCE 700 1- Turov V. Pisarzhevskii Physical Chemistry Institute, Ukrainian Academy of Sciences, Kiev aut NATIONALLICENCE 773 0- Theoretical and Experimental Chemistry Kluwer Academic Publishers-Plenum Publishers 26/1(1990-01-01), 98-101 0040-5760 26:1<98 1990 26 11237 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer