caa a22 4500 465811809 CHVBK 20180323112118.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF02377370 doi (NATIONALLICENCE)springer-10.1007/BF02377370 Histological study of effect of bone morphogenetic protein derived from bovine tooth on periosteum in rats [Elektronische Daten] [Masatoshi Chiba, Takashi Shigihara, Seishi Echigo, Teiichi Teshima] Summary: In this study, we examined histologically the effect of a bone morphogenetic protein (BMP) derived from bovine tooth on the periosteum. Supraperiosteal injection of crude BMP into femurs of Wistar rats (28 day old) resulted in periosteal cell proliferation with subsequent bone and cartilage formation. Moreover, proliferating periosteal cells migrated into injected BMP, and formed both cartilage and bone. These observations show that exogenous BMP stimulates mesenchymal cells of the periosteum to proliferate and differentiate into osteoblasts, and therefore BMP may be one of factors which are involved in differentiation of osteoblasts in the periosteum. Japanese Society of Bone Metabolism Research, 1990 Bone morphogenetic protein-Tooth-Periosteum nationallicence Chiba Masatoshi Second Department of Oral Surgery, Tohoku University School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan aut Shigihara Takashi Second Department of Oral Surgery, Tohoku University School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan aut Echigo Seishi Second Department of Oral Surgery, Tohoku University School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan aut Teshima Teiichi Second Department of Oral Surgery, Tohoku University School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan aut Journal of Bone and Mineral Metabolism Springer-Verlag 8/3(1990-12-01), 24-29 0914-8779 8:3<24 1990 8 774 https://doi.org/10.1007/BF02377370 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02377370 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chiba Masatoshi Second Department of Oral Surgery, Tohoku University School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan aut NATIONALLICENCE 700 1- Shigihara Takashi Second Department of Oral Surgery, Tohoku University School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan aut NATIONALLICENCE 700 1- Echigo Seishi Second Department of Oral Surgery, Tohoku University School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan aut NATIONALLICENCE 700 1- Teshima Teiichi Second Department of Oral Surgery, Tohoku University School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan aut NATIONALLICENCE 773 0- Journal of Bone and Mineral Metabolism Springer-Verlag 8/3(1990-12-01), 24-29 0914-8779 8:3<24 1990 8 774 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer