caa a22 4500 465811892 CHVBK 20180323112118.0 cr unu---uuuuu 170327e19900801xx s 000 0 eng 10.1007/BF02377309 doi (NATIONALLICENCE)springer-10.1007/BF02377309 Effects of oyster shell electrolysate (active absorbable calcium) as a phosphate binder [Elektronische Daten] [Yasuki Hashimoto, Masaaki Fukase, Tatsuo Tsukamoto, Yoshihiro Yamamoto, Kazuto Ikeda, Masamichi Nakai, Tadao Fujimi, Takuo Fujita] Effect of oral calcium load on calcium metabolism was studied in 6 healthy subjects. Calcium carbonate (3.75 g) and Oyster Shell Electrolysate (OSE, 3.0 g) were orally administrated in a cross-over design to provide 1.5 g elementary calcim to each subject twice at 1 week interval. No significant differences were found in the increments of serum calcium, blood ionized calcium and urinary calcium excretion and in the decrements of serum PTH and urinary phosphorus excretion. The decrease in serum phosphorus level after OSE administration, however, was significantly greater than that after calcium carbonate administration. OSE thus appears to have a more potent phosphate binding capacity than calcium carbonate despite indistinguishable immediate effects on the increments of serum calcium and suppression of serum PTH. OSE may therefore represent a new candidate for a potent phosphate binder with a prospect for replacing calcium carbonate currently on use in chronic renal failure. Japanese Society of Bone Metabolism Research, 1990 Oyster Shell Electrolysate nationallicence Active Absorbable Calcium nationallicence Phosphate Binder nationallicence Hashimoto Yasuki Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut Fukase Masaaki Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut Tsukamoto Tatsuo Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut Yamamoto Yoshihiro Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut Ikeda Kazuto Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut Nakai Masamichi Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut Fujimi Tadao Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut Fujita Takuo Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut Journal of Bone and Mineral Metabolism Springer-Verlag 8/2(1990-08-01), 21-25 0914-8779 8:2<21 1990 8 774 https://doi.org/10.1007/BF02377309 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02377309 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hashimoto Yasuki Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut NATIONALLICENCE 700 1- Fukase Masaaki Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut NATIONALLICENCE 700 1- Tsukamoto Tatsuo Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut NATIONALLICENCE 700 1- Yamamoto Yoshihiro Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut NATIONALLICENCE 700 1- Ikeda Kazuto Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut NATIONALLICENCE 700 1- Nakai Masamichi Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut NATIONALLICENCE 700 1- Fujimi Tadao Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut NATIONALLICENCE 700 1- Fujita Takuo Third Division, Department of Medicine, Kobe University School of Medicine, Japan aut NATIONALLICENCE 773 0- Journal of Bone and Mineral Metabolism Springer-Verlag 8/2(1990-08-01), 21-25 0914-8779 8:2<21 1990 8 774 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer