caa a22 4500 465812481 CHVBK 20180323112120.0 cr unu---uuuuu 170327e19901001xx s 000 0 eng 10.1007/BF03190220 doi (NATIONALLICENCE)springer-10.1007/BF03190220 Random drug excess [Elektronische Daten] [U. Helfenstein, M. Steiner] Summary: If a patient is treated in a hospital, drugs are administered at <<deterministic>>, known times. However, if the patient is not supervised the times of drug intake may be less <<deterministic>> and less well known. It seems therefore worthwhile to make a theoretical experiment in which one assumes that drugs are applied according to a random process. In the present article it is proposed that shot noise models could be used to represent concentration curves in such situations. By means of Monte Carlo methods different measures of random drug excess are described. An included program may encourage readers to consider these methods and to perform computer experiments. Springer-Verlag, 1990 Random drug excess nationallicence safety of drugs nationallicence shot noise models nationallicence crossing measures nationallicence Monte Carlo methods nationallicence Helfenstein U. Biostatistisches Zentrum der Medizinischen Fakultät, Universität Zürich, Plattenstrasse 54, CH-8032, Zürich, Switzerland aut Steiner M. Zahnärztliches Institut, Universität Zürich, Zürich, Switzerland aut European Journal of Drug Metabolism and Pharmacokinetics Springer-Verlag 15/4(1990-10-01), 309-315 0378-7966 15:4<309 1990 15 13318 https://doi.org/10.1007/BF03190220 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03190220 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Helfenstein U. Biostatistisches Zentrum der Medizinischen Fakultät, Universität Zürich, Plattenstrasse 54, CH-8032, Zürich, Switzerland aut NATIONALLICENCE 700 1- Steiner M. Zahnärztliches Institut, Universität Zürich, Zürich, Switzerland aut NATIONALLICENCE 773 0- European Journal of Drug Metabolism and Pharmacokinetics Springer-Verlag 15/4(1990-10-01), 309-315 0378-7966 15:4<309 1990 15 13318 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer