caa a22 4500 46581249X CHVBK 20180323112120.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF03190192 doi (NATIONALLICENCE)springer-10.1007/BF03190192 Sanders L. Syntex Research, 3401 Hillview Ave, 94303, Palo Alto, CA, USA aut Drug delivery systems and routes of administration of peptide and protein drugs [Elektronische Daten] [L. Sanders] Summary: The unique requirements of peptides and proteins in designing delivery systems, and the unprecedented recent growth in the field, has driven a great deal of research into novel means of drug delivery. The search for approaches that provide formulations that are stable, bioavailable, readily manufacturable, and acceptable to the patient, has led to major advances in development of nasal and controlled release technology. The field of parenteral solution technology has also seen some new demands made of it, and what was formerly a conventional area of formulation technology has made scientific advances to meet the needs of these compounds. At the same time, strides are being made in fundamental research in areas including oral delivery, transdermal delivery, and pulsatile and ‘on demand' delivery of peptides and proteins. Springer-Verlag, 1990 Peptide delivery nationallicence protein delivery nationallicence controlled release nationallicence systemic delivery nationallicence protein formulation nationallicence delivery routes nationallicence European Journal of Drug Metabolism and Pharmacokinetics Springer-Verlag 15/2(1990-04-01), 95-102 0378-7966 15:2<95 1990 15 13318 https://doi.org/10.1007/BF03190192 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03190192 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Sanders L. Syntex Research, 3401 Hillview Ave, 94303, Palo Alto, CA, USA aut NATIONALLICENCE 773 0- European Journal of Drug Metabolism and Pharmacokinetics Springer-Verlag 15/2(1990-04-01), 95-102 0378-7966 15:2<95 1990 15 13318 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer