caa a22 4500 465812554 CHVBK 20180323112120.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF03190197 doi (NATIONALLICENCE)springer-10.1007/BF03190197 Prodrugs for the improvement of drug absorption via different routes of administration [Elektronische Daten] [L. Balant, E. Doelker, P. Buri] Summary: The authors critically review recent knowledge on the use of prodrugs to improve drug absorption. Main emphasis is placed on the parenteral, oral, transdermal and ocular routes. Mechanisms for drug absorption enhancement and bioavailability assessment are discussed. Some other applications of prodrugs are also examined. Finally, some comments are made regarding the present situation and future trends in prodrug design and their implications in biopharmaceutics and pharmacokinetics. Springer-Verlag, 1990 Pro nationallicence drugs nationallicence absorption improvement nationallicence parenteral route nationallicence oral route nationallicence transdermal route nationallicence ocular route nationallicence bioavailability nationallicence Balant L. Department of Psychiatry, Geneva University Hospital, 1211, Geneva 4, Switzerland aut Doelker E. School of Pharmacy, University of Geneva, Switzerland aut Buri P. School of Pharmacy, University of Geneva, Switzerland aut European Journal of Drug Metabolism and Pharmacokinetics Springer-Verlag 15/2(1990-04-01), 143-153 0378-7966 15:2<143 1990 15 13318 https://doi.org/10.1007/BF03190197 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF03190197 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Balant L. Department of Psychiatry, Geneva University Hospital, 1211, Geneva 4, Switzerland aut NATIONALLICENCE 700 1- Doelker E. School of Pharmacy, University of Geneva, Switzerland aut NATIONALLICENCE 700 1- Buri P. School of Pharmacy, University of Geneva, Switzerland aut NATIONALLICENCE 773 0- European Journal of Drug Metabolism and Pharmacokinetics Springer-Verlag 15/2(1990-04-01), 143-153 0378-7966 15:2<143 1990 15 13318 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer