caa a22 4500 465820700 CHVBK 20180323112135.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF01233200 doi (NATIONALLICENCE)springer-10.1007/BF01233200 Localization of gene for human syndecan, an integral membrane proteoglycan and a matrix receptor, to chromosome 2 [Elektronische Daten] [M. Ala-Kapee, H. Nevanlinna, M. Mali, M. Jalkanen, J. Schröder] Syndecan, a cell surface proteoglycan, is an integral membrane protein acting as a receptor for the extracellular matrix. For chromosomal localization of the human syndecan gene, a panel of mouse-human somatic cell hybrids was analyzed by Southern blotting using the cDNA probe for human syndecan. The hybrids were karyotyped at the time of DNA extraction. A band corresponding to the human syndecan gene in Southern blots was found only in a hybrid cell line containing human chromosome 2. This hybrid was subcloned and its subclones were analyzed by Southern blotting and karyotyped. Subclones carrying human chromosome 2 contained the syndecan gene, while subclones not carrying this chromosome did not. The human syndecan gene is thus assigned to chromosome 2. Plenum Publishing Corporation, 1990 Ala-Kapee M. Department of Genetics, University of Helsinki, Helsinki, Finland aut Nevanlinna H. Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland aut Mali M. Department of Medical Biochemistry, University of Turku, Turku, Finland aut Jalkanen M. Department of Medical Biochemistry, University of Turku, Turku, Finland aut Schröder J. Department of Genetics, University of Helsinki, Helsinki, Finland aut Somatic Cell and Molecular Genetics Kluwer Academic Publishers-Plenum Publishers 16/5(1990-09-01), 501-505 0740-7750 16:5<501 1990 16 11188 https://doi.org/10.1007/BF01233200 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01233200 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ala-Kapee M. Department of Genetics, University of Helsinki, Helsinki, Finland aut NATIONALLICENCE 700 1- Nevanlinna H. Department of Obstetrics and Gynecology, University of Helsinki, Helsinki, Finland aut NATIONALLICENCE 700 1- Mali M. Department of Medical Biochemistry, University of Turku, Turku, Finland aut NATIONALLICENCE 700 1- Jalkanen M. Department of Medical Biochemistry, University of Turku, Turku, Finland aut NATIONALLICENCE 700 1- Schröder J. Department of Genetics, University of Helsinki, Helsinki, Finland aut NATIONALLICENCE 773 0- Somatic Cell and Molecular Genetics Kluwer Academic Publishers-Plenum Publishers 16/5(1990-09-01), 501-505 0740-7750 16:5<501 1990 16 11188 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer