caa a22 4500 465820883 CHVBK 20180323112135.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF01233044 doi (NATIONALLICENCE)springer-10.1007/BF01233044 A human ADP/ATP translocase gene has seven pseudogenes and localizes to chromosome X [Elektronische Daten] [Sing-Tsung Chen, Chung-Der Chang, Kay Huebner, De-Hui Ku, Michael McFarland, J. DeRiel, Renato Baserga, John Wurzel] There are at least three transcriptionally active human ADP/ATP translocase genes. We have isolated seven ADP/ATP translocase pseudogenes from recombinant human genomic libraries. Each pseudogene sequence had more than 85% identity with the sequence of the human ADP/ATP translocase cDNA derived from fibroblast mRNA, but each had mutations that precluded synthesis of a functional protein. Using an intro probe derived from a partial clone of the human fibroblast ADP/ATP translocase gene, we localized the gene to chromosome Xq13 → Xq25-26. The gene encoding the skeletal muscle translocase has previously been shown to be on chromosome 4. Therefore, the human ADP/ATP translocase genes are members of a multigene family that includes pseudogenes and has been dispersed to at least two chromosomes. Plenum Publishing Corporation, 1990 Chen Sing-Tsung Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut Chang Chung-Der Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut Huebner Kay Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut Ku De-Hui Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut McFarland Michael Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut DeRiel J. Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut Baserga Renato Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut Wurzel John Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut Somatic Cell and Molecular Genetics Kluwer Academic Publishers-Plenum Publishers 16/2(1990-03-01), 143-149 0740-7750 16:2<143 1990 16 11188 https://doi.org/10.1007/BF01233044 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01233044 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chen Sing-Tsung Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut NATIONALLICENCE 700 1- Chang Chung-Der Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut NATIONALLICENCE 700 1- Huebner Kay Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut NATIONALLICENCE 700 1- Ku De-Hui Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut NATIONALLICENCE 700 1- McFarland Michael Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut NATIONALLICENCE 700 1- DeRiel J. Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut NATIONALLICENCE 700 1- Baserga Renato Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut NATIONALLICENCE 700 1- Wurzel John Department of Pathology, and Fels Institute for Cancer Research and Molecular Biology, Temple University Medical School, Philadelphia, Pennsylvania aut NATIONALLICENCE 773 0- Somatic Cell and Molecular Genetics Kluwer Academic Publishers-Plenum Publishers 16/2(1990-03-01), 143-149 0740-7750 16:2<143 1990 16 11188 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer