caa a22 4500 465821790 CHVBK 20180323112137.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF00047551 doi (NATIONALLICENCE)springer-10.1007/BF00047551 Burgio G. Paediatric Department, University of Pavia, Italy aut The "biological ego”. From Garrod's " chemical individuality ” to Burnet's " self ” [Elektronische Daten] [G. Burgio] Starting from the conceptual premises of Garrod, who as long ago as 1902 spoke of "chemical individuality”, and of Burnet (1949), who recognized as self one's own molecular antigenic structures (as opposed to the antigenic "alien”: the non- self), the discovery and understanding of HLA antigens and of their extraordinarily individual and differentiated polymorphisms have gained universal recognition. Transplant medicine has now dramatically stressed, within man's knowledge of himself, the characteristic of his "biological uniqueness”. Today man, having become aware of being a biological antigenic-molecular individuality which is unique and different from that of all of his fellow men (except for monozygotic twins), can therefore easily consider himself a true "biological Ego”. Kluwer Academic Publishers, 1990 antigenic individuality nationallicence antigenic uniqueness nationallicence biological Ego nationallicence chimera nationallicence self-nonself recognition nationallicence transplant immunity nationallicence BMT : bone marrow transplantation nationallicence GVHD : graft versus host disease nationallicence HLA : human leukocyte antigens nationallicence MHC : major histocompatibility complex nationallicence MLC : mixed lymphocyte culture nationallicence MLR : mixed lymphocyte reaction nationallicence Acta Biotheoretica Kluwer Academic Publishers 38/2(1990-06-01), 143-159 0001-5342 38:2<143 1990 38 10441 https://doi.org/10.1007/BF00047551 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00047551 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Burgio G. Paediatric Department, University of Pavia, Italy aut NATIONALLICENCE 773 0- Acta Biotheoretica Kluwer Academic Publishers 38/2(1990-06-01), 143-159 0001-5342 38:2<143 1990 38 10441 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer