caa a22 4500 465822460 CHVBK 20180323112139.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00903770 doi (NATIONALLICENCE)springer-10.1007/BF00903770 Control of the selectivity of butyric acid production and improvement of fermentation performance with Clostridium tyrobutyricum [Elektronische Daten] [D. Michel-Savin, R. Marchal, J. Vandecasteele] Summary: The parameters that control fermentation performance of butyrate production have been studied with a selected strain ofClostridium tyrobutyricum. Fed-batch supply of glucose increased productivity for butyrate. The ratio of butyrate to total acids was strongly influenced by the growth rate of the bacteria, acetate being produced along with butyrate at higher growth rates. In glucose-limited, fed-batch cultures, initially produced acetate was re-utilized, resulting in exclusive production of butyrate. In cultures with non-limiting glucose feeding, the butyrate concentration reached 42.5 g·1−1 with a selectivity of 0.90, a productivity of 0.82 g·−1 per hour and a yield of 0.36 g·g−1 The effects of the mode of supply of glucose on the production of butyrate and acetate are discussed in relation with the energy requirements for cell growth. Springer-Verlag, 1990 Michel-Savin D. Direction de Recherche Biotechnologie et Environnement, Institut Français du Pétrole, F-92506, Rueil-Malmaison, France aut Marchal R. Direction de Recherche Biotechnologie et Environnement, Institut Français du Pétrole, F-92506, Rueil-Malmaison, France aut Vandecasteele J. Direction de Recherche Biotechnologie et Environnement, Institut Français du Pétrole, F-92506, Rueil-Malmaison, France aut Applied Microbiology and Biotechnology Springer-Verlag 32/4(1990-01-01), 387-392 0175-7598 32:4<387 1990 32 253 https://doi.org/10.1007/BF00903770 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00903770 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Michel-Savin D. Direction de Recherche Biotechnologie et Environnement, Institut Français du Pétrole, F-92506, Rueil-Malmaison, France aut NATIONALLICENCE 700 1- Marchal R. Direction de Recherche Biotechnologie et Environnement, Institut Français du Pétrole, F-92506, Rueil-Malmaison, France aut NATIONALLICENCE 700 1- Vandecasteele J. Direction de Recherche Biotechnologie et Environnement, Institut Français du Pétrole, F-92506, Rueil-Malmaison, France aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer-Verlag 32/4(1990-01-01), 387-392 0175-7598 32:4<387 1990 32 253 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer