caa a22 4500 465822487 CHVBK 20180323112139.0 cr unu---uuuuu 170327e19900201xx s 000 0 eng 10.1007/BF00173734 doi (NATIONALLICENCE)springer-10.1007/BF00173734 Bacterial metabolism of side-chain-fluorinated aromatics: unproductive meta-cleavage of 3-trifluoromethylcatechol [Elektronische Daten] [Karl-Heinrich Engesser, Miguel Rubio, Hans-Joachim Knackmuss] Summary: Sixteen bacterial strains capable of degrading alkylbenzenes and alkylphenols were directly isolated from soil and water. The degradation pathways are discussed. Alkylcatechols are almost exclusively cleaved via meta-ring fission. Meta-cleavage of 3-trifluoromethyl-(TFM)-catechol was observed with all strains at different rates although the reaction rates compared to catechol as a substrate varied considerably. All 2-hydroxy-6-oxohepta-2,4-dienoic acid hydrolases investigated showed strong binding of 7,7,7-trifluoro-2-hydroxy-6-oxohepta-2,4-dienoic acid, the ring fission product of 3-TFM-catechol. Turnover rates, however, were negligible indicating this compound to be a general dead-end metabolite during metabolism of TFM-substituted compounds via meta-cleavage pathways. Springer-Verlag, 1990 Engesser Karl-Heinrich Institut für Mikrobiologie der Universität Stuttgart, Azenbergstrasse 18, D-7000, Stuttgart-1, Federal Republic of Germany aut Rubio Miguel Technische Universität Hamburg-Harburg, Abteilung für Gewässerreinigungstechnik, D-2100, Hamburg 90, Federal Republic of Germany aut Knackmuss Hans-Joachim Institut für Mikrobiologie der Universität Stuttgart, Azenbergstrasse 18, D-7000, Stuttgart-1, Federal Republic of Germany aut Applied Microbiology and Biotechnology Springer-Verlag 32/5(1990-02-01), 600-608 0175-7598 32:5<600 1990 32 253 https://doi.org/10.1007/BF00173734 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00173734 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Engesser Karl-Heinrich Institut für Mikrobiologie der Universität Stuttgart, Azenbergstrasse 18, D-7000, Stuttgart-1, Federal Republic of Germany aut NATIONALLICENCE 700 1- Rubio Miguel Technische Universität Hamburg-Harburg, Abteilung für Gewässerreinigungstechnik, D-2100, Hamburg 90, Federal Republic of Germany aut NATIONALLICENCE 700 1- Knackmuss Hans-Joachim Institut für Mikrobiologie der Universität Stuttgart, Azenbergstrasse 18, D-7000, Stuttgart-1, Federal Republic of Germany aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer-Verlag 32/5(1990-02-01), 600-608 0175-7598 32:5<600 1990 32 253 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer