caa a22 4500 465822932 CHVBK 20180323112140.0 cr unu---uuuuu 170327e19901001xx s 000 0 eng 10.1007/BF00170929 doi (NATIONALLICENCE)springer-10.1007/BF00170929 Stimulatory effect of glycine betaine on l -lysine fermentation [Elektronische Daten] [Yoshio Kawahara, Yasuhiko Yoshihara, Shigeho Ikeda, Hiroe Yoshii, Yoshio Hirose] Summary: The growth rate, sugar consumption rate, and production rate of an l-lysine producing Brevibacterium lactofermentum mutant were stimulated by addition of exogenous glycine betaine. Glycine betaine stimulated the growth rate especially in media of inhibitory osmotic stress, and the stimulation was independent of any specific solute. Therefore growth stimulation by glycine betaine was considered to be an osmoprotective effect. A strong enhancement of the sugar consumption rate and the l-lysine production rate was observed even with resting cells under osmotic stress as well as in a fermentation with growing cells. These data indicated that the osmoprotective effects of glycine betaine on l-lysine production can be independent of protein synthesis. Springer-Verlag, 1990 Kawahara Yoshio Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut Yoshihara Yasuhiko Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut Ikeda Shigeho Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut Yoshii Hiroe Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut Hirose Yoshio Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut Applied Microbiology and Biotechnology Springer-Verlag 34/1(1990-10-01), 87-90 0175-7598 34:1<87 1990 34 253 https://doi.org/10.1007/BF00170929 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00170929 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kawahara Yoshio Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut NATIONALLICENCE 700 1- Yoshihara Yasuhiko Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut NATIONALLICENCE 700 1- Ikeda Shigeho Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut NATIONALLICENCE 700 1- Yoshii Hiroe Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut NATIONALLICENCE 700 1- Hirose Yoshio Technology and Engineering Center of Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, 210, Kawasaki-shi, Japan aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer-Verlag 34/1(1990-10-01), 87-90 0175-7598 34:1<87 1990 34 253 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer