caa a22 4500 465822983 CHVBK 20180323112141.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF00170060 doi (NATIONALLICENCE)springer-10.1007/BF00170060 Ishiyama Jiro Research and Development Division, Kikkoman Corporation, 278, Noda-shi, Chiba-ken, Japan aut Isolation of mutants with improved production of cAMP from Microbacterium sp. no. 205 (ATCC21376) [Elektronische Daten] [Jiro Ishiyama] Summary: Mutants were isolated from Microbacterium sp. no. 205 (ATCC 21376) producing 13-30mm cyclic adenosine 3′,5′-monophosphate (cAMP) by salvage biosynthesis, through sequential improvements of the bacterium for the purpose of improving cAMP production. The mutants produced 50-75 mm cAMP on 100 mm inosine 5′-monophosphate as a precursor. Mutants resistant to the inhibition of growth by cAMP at high concentrations were isolated; the resistance was one of four characteristics effective for improved production of cAMP. Springer-Verlag, 1990 Applied Microbiology and Biotechnology Springer-Verlag 34/3(1990-12-01), 359-363 0175-7598 34:3<359 1990 34 253 https://doi.org/10.1007/BF00170060 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00170060 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Ishiyama Jiro Research and Development Division, Kikkoman Corporation, 278, Noda-shi, Chiba-ken, Japan aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer-Verlag 34/3(1990-12-01), 359-363 0175-7598 34:3<359 1990 34 253 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer