caa a22 4500 465823416 CHVBK 20180323112142.0 cr unu---uuuuu 170327e19901101xx s 000 0 eng 10.1007/BF00166771 doi (NATIONALLICENCE)springer-10.1007/BF00166771 d (−)lactic acid production by suspended and aggregated continuous cultures of Bacillus laevolacticus [Elektronische Daten] [Jan de Boer, M. de Mattos Teixeira, O. Neijssel] Summary: A new method of d(−)lactic acid production based on the aggregated form of growth of Bacillus laevolacticus in continuous culture in an anaerobic gaslift reactor is presented. With glucose as the substrate a bacterial dry weight of 25 g·1−1 and a lactic acid production rate of 13 g·1−1·h−1 was attained. In conventional glucose-limited chemostat cultures elevated levels of lactic acid stimulated specific lactic acid production while the formation rates of other end-products remained unaffected. In glucose-limited aggregated cultures lactic acid positively influenced the aggregation of cells, improving the volumetric production rate. It is concluded that lactic acid itself is a positive effector in the optimisation of lactic acid production with aggregated cultures of B. laevolacticus. Springer-Verlag, 1990 de Boer Jan Department of Microbiology, Biotechnology Center, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands aut de Mattos Teixeira M. Department of Microbiology, Biotechnology Center, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands aut Neijssel O. Department of Microbiology, Biotechnology Center, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands aut Applied Microbiology and Biotechnology Springer-Verlag 34/2(1990-11-01), 149-153 0175-7598 34:2<149 1990 34 253 https://doi.org/10.1007/BF00166771 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00166771 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- de Boer Jan Department of Microbiology, Biotechnology Center, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- de Mattos Teixeira M. Department of Microbiology, Biotechnology Center, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Neijssel O. Department of Microbiology, Biotechnology Center, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer-Verlag 34/2(1990-11-01), 149-153 0175-7598 34:2<149 1990 34 253 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer