caa a22 4500 465824315 CHVBK 20180323112144.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF00176665 doi (NATIONALLICENCE)springer-10.1007/BF00176665 Influence of the reaction medium on the product distribution of peroxidase-catalysed oxidation of p -cresol [Elektronische Daten] [Pekka Pietikäinen, Patrick Adlercreutz] Summary: p-Cresol was oxidized by hydrogen peroxide in a reaction catalysed by horseradish peroxidase and the low molecular weight products were investigated. In aqueous media Pummerer's ketone (I) was the dominating product but in organic media the product distribution was quite different; 2,2'-dihydroxy-5,5'-dimethyldiphenyl (II) was the main low molecular weight product. Similar product distributions were obtained with peroxidase adsorbed on a solid support and suspended in toluene and with peroxidase solubilized in a microemulsion containing the same solvent. The best selectivity for the formation of (II) was obtained when the enzyme was adsorbed on Celite and suspended in water-saturated chloroform with 0.5% (v/v) extra water added. The yield of low molecular weight products in this case was 28%; of this fraction, 95% was (II). Springer-Verlag, 1990 Pietikäinen Pekka Department of Biotechnology, Chemical Center, University of Lund, P.O. Box 124, S-22100, Lund, Sweden aut Adlercreutz Patrick Department of Biotechnology, Chemical Center, University of Lund, P.O. Box 124, S-22100, Lund, Sweden aut Applied Microbiology and Biotechnology Springer-Verlag 33/4(1990-07-01), 455-458 0175-7598 33:4<455 1990 33 253 https://doi.org/10.1007/BF00176665 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00176665 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pietikäinen Pekka Department of Biotechnology, Chemical Center, University of Lund, P.O. Box 124, S-22100, Lund, Sweden aut NATIONALLICENCE 700 1- Adlercreutz Patrick Department of Biotechnology, Chemical Center, University of Lund, P.O. Box 124, S-22100, Lund, Sweden aut NATIONALLICENCE 773 0- Applied Microbiology and Biotechnology Springer-Verlag 33/4(1990-07-01), 455-458 0175-7598 33:4<455 1990 33 253 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer