caa a22 4500 465825710 CHVBK 20180323112148.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF02832145 doi (NATIONALLICENCE)springer-10.1007/BF02832145 Transcutaneous Pco2 and Po2: A multicenter study of accuracy [Elektronische Daten] [Barbara Palmisano, John Severinghaus] A multicentcr study used 756 samples from 251 patients in 12 institutions to compare arterial (PaO2, PaCO2) with transcutaneous (PsO2, PsCO2) oxygen and carbon dioxide tensions, measured usually at 44°C. Of these samples, 336 were obtained from 116 neonates, 27 from 25 children with cystic fibrosis, and 140 from 40 patients under general anesthesia. Ninety-one patients were between 4 weeks and 18 years of age, 32 were between 18 and 60 years, and 12 were over 60. The ratio of transcutaneous to arterial P(s/a)CO2 was 1.01 ±0.11 with PaCO2 less than 30 mm Hg, increasing to 1.04 ±0.08 at PaCO2 greater than 40 mm Hg. Mean bias and its standard deviation (PsCO2 — PaCO2) were + 1.3 ± 3.9 mm Hg in the entire group, + 1.8 ± 4.2 mm Hg in neonates (NS). Bias was +0.2 ± 2.7 mm Hg when PaCO2 was less than 30 mm Hg (N = 175, NS), 1.0 ± 3.4 with 30 < PaCO2 < 40 (n = 329,p < 0.001), and +2.04 ± 4.00 mm Hg with 40 < PaCO2 < 70 (n = 229,p < 0.001). These data suggest that, using transcutaneous PCO2 monitors with inbuilt temperature correction of 4.5%/‡C, the skin metabolic offset should be set to 6 mm Hg. The linear regression was PsCO2 =1.052(PaCO2)-0.56, Sy·x = 3.92, R = 0.929 (n = 756); and PsCO2 = 1.09(PaCO2)-1.57, Sy·x = 4.17, R = 0.928 in neonates (n = 336). The use of vasopressors and vasodilators had no significant effect on bias or its standard deviation or on regression slope and intercept (n = 78). In cystic fibrosis patients, bias and standard deviation were 0.0 ± 1.7 mm Hg (n = 27). Under anesthesia, PsCO2 = 1.07PaCO2-1.58, with bias and standard deviation = 0.6 ± 3.5 (n = 140). For oxygen, at PaO2 ≤ 80 the ratio P(s/a)O2 = 1.05 ± 0.16 in nconates and 0.93 ± 0.21 in older patients, but when PaO2 > 80, P(s/a)O2 fell to 0.88 ± 0.18 in neonates and 0.74 ± 0.21 in older patients. The errors were significantly greater (p < 0.001) in older patients than in neonates above but not below 80 mm Hg, and within both groups errors were significantly greater above than below 80 mm Hg. Little, Brown and Company, 1990 Monitoring nationallicence Measurement techniques: blood gases nationallicence Blood gas analysis nationallicence Palmisano Barbara Departments of Anesthesia and Pediatrics, Medical College of Wisconsin, Milwaukee, WI aut Severinghaus John Department of Anesthesia and the Cardiovascular Research Institute, University of California, 94143-0542, San Francisco, CA aut Journal of Clinical Monitoring Springer Netherlands 6/3(1990-07-01), 189-195 0748-1977 6:3<189 1990 6 10877 https://doi.org/10.1007/BF02832145 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02832145 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Palmisano Barbara Departments of Anesthesia and Pediatrics, Medical College of Wisconsin, Milwaukee, WI aut NATIONALLICENCE 700 1- Severinghaus John Department of Anesthesia and the Cardiovascular Research Institute, University of California, 94143-0542, San Francisco, CA aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring Springer Netherlands 6/3(1990-07-01), 189-195 0748-1977 6:3<189 1990 6 10877 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer