caa a22 4500 465825729 CHVBK 20180323112148.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF02832154 doi (NATIONALLICENCE)springer-10.1007/BF02832154 Engineering implications of closed-loop control during cardiac surgery [Elektronische Daten] [A. Sebald, M. Quinn, N. Smith, A. Karimi, G. Schnurer, S. Isaka] Conclusions: 1 Closed loop control in cardiac surgery is a very difficult problem because of changes in patient response, substantial nonrandom external disturbances, random disturbances, and relatively long pure delays between infusion by the pump and initiation of bodily response. 2 System identification models based on real data are crucial for quantitatively describing the relationships encountered in practice. 3 A minimax approach is useful for mathematically describing the control design process as an attempt to choose a single controller capable of coping with a set of patients. It also yields computer-aided design tools. 4 Typical real controllers in complex environments like cardiac surgery contain relatively large numbers of parameters that must be specified. A computer algorithm capable of performing minimax analysis on such problems is available [4]. 5 Design of controllers for complex environments such as cardiac surgery requires the use of computeraided design tools for proper performance. The complexity of the problem and the number of possible combinations of control parameters and architecture may make less exhaustive manual simulation approaches unproductive. 6 Computer-aided design tools are extremely important because they permit much more exhaustive testing prior to application on animals and humans. They permit evaluation of literally millions of combinations of patients and controllers at computer speeds. Manual design searches cannot be done for these large problems. Little, Brown and Company, 1990 Surgery: cardiac nationallicence Sebald A. College of Engineering, University of California San Diego, San Diego, CA aut Quinn M. Department of Anesthesiology, University of California San Diego, San Diego, CA aut Smith N. Department of Anesthesiology, University of California San Diego, San Diego, CA aut Karimi A. Department of Applied Mechanical/Engineering Sciences, University of California San Diego, San Diego, CA aut Schnurer G. Department of Applied Mechanical/Engineering Sciences, University of California San Diego, San Diego, CA aut Isaka S. Department of Applied Mechanical/Engineering Sciences, University of California San Diego, San Diego, CA aut Journal of Clinical Monitoring Springer Netherlands 6/3(1990-07-01), 241-248 0748-1977 6:3<241 1990 6 10877 https://doi.org/10.1007/BF02832154 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02832154 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sebald A. College of Engineering, University of California San Diego, San Diego, CA aut NATIONALLICENCE 700 1- Quinn M. Department of Anesthesiology, University of California San Diego, San Diego, CA aut NATIONALLICENCE 700 1- Smith N. Department of Anesthesiology, University of California San Diego, San Diego, CA aut NATIONALLICENCE 700 1- Karimi A. Department of Applied Mechanical/Engineering Sciences, University of California San Diego, San Diego, CA aut NATIONALLICENCE 700 1- Schnurer G. Department of Applied Mechanical/Engineering Sciences, University of California San Diego, San Diego, CA aut NATIONALLICENCE 700 1- Isaka S. Department of Applied Mechanical/Engineering Sciences, University of California San Diego, San Diego, CA aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring Springer Netherlands 6/3(1990-07-01), 241-248 0748-1977 6:3<241 1990 6 10877 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer