caa a22 4500 465825850 CHVBK 20180323112148.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF02832143 doi (NATIONALLICENCE)springer-10.1007/BF02832143 Oxygen uptake and mean blood pressure as indicators of induced hyperthermia [Elektronische Daten] [V. de las Alas, L. Geddes, W. Voorhees, J. Bourland, W. Schoenlein] This dog study was designed to identify which of two measurements (oxygen consumption, mean blood pressure) tracked the onset of hyperthermia as reflected by rectal temperature. The animals were anesthetized, paralyzed, and mechanically ventilated. Hyperthermia was induced with 2,4-dinitrophenol (5 mg/kg) injected intravenously in 5 dogs. It was found that the best and earliest predictor of approaching hyperthermia was the increase in oxygen consumption, which increased 10% in 1.72 min. Mean blood pressure was an insensitive indicator of approaching hyperthermia. Rectal temperature, not surprisingly, was found to be a late and undependable early indicator of developing hyperthermia, requiring about 15 minutes to exhibit a definite increase. It is concluded that among these indicators, monitoring oxygen consumption (ml/min) is the most reliable way to identify a metabolic change such as incipient hyperthermia. Little, Brown and Company, 1990 Hyperthermia nationallicence Measurement techniques: blood nationallicence pressure nationallicence Oxygen: uptake nationallicence Monitoring: oxygen nationallicence blood pressure nationallicence de las Alas V. University of Michigan Hospitals, Ann Arbor, MI aut Geddes L. Hillenbrand Biomedical Engineering Center, Purdue University, AA Potter Building, Room 204, 47907, West Lafayette, IN aut Voorhees W. Hillenbrand Biomedical Engineering Center, Purdue University, AA Potter Building, Room 204, 47907, West Lafayette, IN aut Bourland J. Hillenbrand Biomedical Engineering Center, Purdue University, AA Potter Building, Room 204, 47907, West Lafayette, IN aut Schoenlein W. Hillenbrand Biomedical Engineering Center, Purdue University, AA Potter Building, Room 204, 47907, West Lafayette, IN aut Journal of Clinical Monitoring Springer Netherlands 6/3(1990-07-01), 186-188 0748-1977 6:3<186 1990 6 10877 https://doi.org/10.1007/BF02832143 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02832143 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- de las Alas V. University of Michigan Hospitals, Ann Arbor, MI aut NATIONALLICENCE 700 1- Geddes L. Hillenbrand Biomedical Engineering Center, Purdue University, AA Potter Building, Room 204, 47907, West Lafayette, IN aut NATIONALLICENCE 700 1- Voorhees W. Hillenbrand Biomedical Engineering Center, Purdue University, AA Potter Building, Room 204, 47907, West Lafayette, IN aut NATIONALLICENCE 700 1- Bourland J. Hillenbrand Biomedical Engineering Center, Purdue University, AA Potter Building, Room 204, 47907, West Lafayette, IN aut NATIONALLICENCE 700 1- Schoenlein W. Hillenbrand Biomedical Engineering Center, Purdue University, AA Potter Building, Room 204, 47907, West Lafayette, IN aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring Springer Netherlands 6/3(1990-07-01), 186-188 0748-1977 6:3<186 1990 6 10877 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer