caa a22 4500 465826105 CHVBK 20180323112149.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF02828282 doi (NATIONALLICENCE)springer-10.1007/BF02828282 Effect of anemia on pulse oximeter accuracy at low saturation [Elektronische Daten] [John Severinghaus, Shin Koh] A retrospective evaluation of simultaneous tests of oximeters of various manufacturers in volunteer subjects disclosed greater errors at low saturations in subjects with low hemoglobin (Hb) concentrations. Forty-three pulse oximcters of 12 manufacturers studied over a period of 10 months showed that, at a mean arterial oxygen saturation (SaO2) level of 54.5%, as Hb concentration fell, average pulse oximeter (SpO2) bias increased approximately linearly from 0 at Hb > 14 g/dl to about -14% at 8 < Hb < 9 g/dl. At SaO2 = 53.6%, the mean bias (SaO2-SpO2) of 13 oximcters of 5 manufacturers averaged -15.0% (n = 43) in a subject with Hb = 8 g/dl, but -6.4% (n = 390) in nonanemic subjects. The additional bias in the anemic subject increased with desaturation. It was 0.13% at SaO2 = 98.5% (n = 13), -1.31% at 87.5% (n = 38), -2.71% at 75.1% (n = 38), -5.18% at 61.3% (n = 26), and -9.95% at 53.6% (n = 41); n is the product of the number of oximeters and number of tests in each saturation range. The instruments that showed the greatest errors at low saturations in nonanemic subjects also showed the greatest additional errors associated with anemia (the range between manufacturers of anemic incremental error at about 53% being from -3.2 to -14.5%) and conformed well to the relationship bias (anemic) = 1.35 × bias (normal)-8.18% (r = 0.94; Sy·x = 3.3%). The error due to anemia was zero at 97% SaO2 and became evident when SaO2 fell below 75%. Little, Brown and Company, 1990 Measurement techniques: pulse oximetry nationallicence Blood: anemia nationallicence Equipment: pulse oximeters nationallicence Oxygen: saturation nationallicence Hypoxia nationallicence Severinghaus John Department of Anesthesia and the Cardiovascular Research Institute, University of California, San Francisco, CA aut Koh Shin Department of Anesthesia and the Cardiovascular Research Institute, University of California, San Francisco, CA aut Journal of Clinical Monitoring Springer Netherlands 6/2(1990-04-01), 85-88 0748-1977 6:2<85 1990 6 10877 https://doi.org/10.1007/BF02828282 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02828282 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Severinghaus John Department of Anesthesia and the Cardiovascular Research Institute, University of California, San Francisco, CA aut NATIONALLICENCE 700 1- Koh Shin Department of Anesthesia and the Cardiovascular Research Institute, University of California, San Francisco, CA aut NATIONALLICENCE 773 0- Journal of Clinical Monitoring Springer Netherlands 6/2(1990-04-01), 85-88 0748-1977 6:2<85 1990 6 10877 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer