caa a22 4500 465826652 CHVBK 20180323112151.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF01075676 doi (NATIONALLICENCE)springer-10.1007/BF01075676 An investigation of the role of circulating catecholamines in the control of ventilation during acute moderate hypoxia in rainbow trout ( Oncorhynchus mykiss ) [Elektronische Daten] [Richard Kinkead, Steve Perry] Summary: Gill ventilation volume ( $$\dot V$$ w), arterial blood oxygen tension (PaO2) and arterial blood oxygen content (CaO2) of rainbow trout (Oncorhyncus mykiss) were monitored during normoxia [waterPO2 (PwO2) ∼155 Torr], hypoxia (PwO2=72±5.8 Torr), or hyperoxia (PwO2=643±32 Torr). Fish hyperventilated during acute (30 min) hypoxia and hypoventilagted during acute hyperoxia. Plasma catecholamine levels were unchanged after 30 min of hypoxia or hyperoxia. In addition, selective adrenoceptor blockade with either propranolol (β-adrenoceptor antagonist) or phentolamine (α-adrenoceptor antagonist) did not modify the hyperventilatory response during hypoxia. These results indicate that circulating catecholamines are not involved in the control of ventilation in moderately hypoxic rainbow trout. In the summer, intra-arterial infusion of catecholamine in normoxic trout caused transient (adrenaline) or persistent (noradrenaline) hypoventilation. These observations also do not support a role for catecholamines in the stimulation of ventilation. During hypoxia,PwO2,PaO2 andCaO2 were depressed whereas during hyperoxia, onlyPwO2 andPaO2 was elevated significantly. Thus, it is suggested that the hypoventilatory response to hyperoxia is mediated by a direct effect of elevatedPwO2/PaO2, whereas the hyperventilatory response to hypoxia is mediated by changes inPwO2/PaO2, and/orCaO2. Springer-Verlag, 1990 Hypoxia nationallicence Hyperoxia nationallicence Catecholamines nationallicence Oncorhyncus mykiss nationallicence Ventilation nationallicence Kinkead Richard Department of Biology, University of Ottawa, 30 George Glinski, K1N 6N5, Ottawa, Ontario, Canada aut Perry Steve Department of Biology, University of Ottawa, 30 George Glinski, K1N 6N5, Ottawa, Ontario, Canada aut Journal of Comparative Physiology B Springer-Verlag 160/4(1990-07-01), 441-448 0174-1578 160:4<441 1990 160 360 https://doi.org/10.1007/BF01075676 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01075676 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kinkead Richard Department of Biology, University of Ottawa, 30 George Glinski, K1N 6N5, Ottawa, Ontario, Canada aut NATIONALLICENCE 700 1- Perry Steve Department of Biology, University of Ottawa, 30 George Glinski, K1N 6N5, Ottawa, Ontario, Canada aut NATIONALLICENCE 773 0- Journal of Comparative Physiology B Springer-Verlag 160/4(1990-07-01), 441-448 0174-1578 160:4<441 1990 160 360 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer