caa a22 4500 467888159 CHVBK 20180406152740.0 cr unu---uuuuu 170328e20060601xx s 000 0 eng 10.1007/s11144-006-0124-1 doi (NATIONALLICENCE)springer-10.1007/s11144-006-0124-1 Carvone epoxidation by system "hydrogen peroxide-[Mn 2 L 2 O 3 ][PF 6 ] 2 (L [Elektronische Daten] 1,4,7-trimethyl-1,4,7-triazacyclononane)-carboxylic acid”: a combinatorial approach to the process optimization [Dalmo Mandelli, Rafael A. Steffen, Georgiy B. Shul'pin] Summary: Epoxidation of natural terpene (+)-carvone by the system consisting of a catalyst, oxalic acid (co-catalyst) and H2O2 (70% aqueous solution; oxidant) was studied and factorial design methods were applied for the optimization of this reaction. A dinuclear manganese(IV) complex [LMn(O)3MnL](PF6)2 (L = 1,4,7-trimethyl-1,4,7-triazacyclononane) was used as a catalyst, and acetonitrile was employed as a solvent. An analysis by methods of the complete 24 factorial design showed that an increase in the catalyst concentration gives a strong positive effect on the carvone conversion and selectivity. Hydrogen peroxide has a smaller positive effect on the conversion, but at high concentration, H2O2 leads to some decrease in the selectivity. An increase in the oxalic acid concentration has a beneficial effect on the conversion, but does not affect the selectivity. Springer-Verlag/Akadémiai Kiadó, 2006 hydrogen peroxide nationallicence optimization nationallicence Epoxidation nationallicence manganese complexes nationallicence homogeneous catalysis nationallicence Mandelli Dalmo Pontifícia Universidade Católica de Campinas, Faculdade de Química, Campus I, Rod. D. Pedro I, km 136, Pq. das Universidades, Campinas, SP, 13086-900, Brazil aut Steffen Rafael A. Pontifícia Universidade Católica de Campinas, Faculdade de Química, Campus I, Rod. D. Pedro I, km 136, Pq. das Universidades, Campinas, SP, 13086-900, Brazil aut Shul'pin Georgiy B. Semenov Institute of Chemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow 119991, Russia aut Reaction Kinetics and Catalysis Letters Kluwer Academic Publishers 88/1(2006-06-01), 165-173 0133-1736 88:1<165 2006 88 11144 https://doi.org/10.1007/s11144-006-0124-1 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s11144-006-0124-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mandelli Dalmo Pontifícia Universidade Católica de Campinas, Faculdade de Química, Campus I, Rod. D. Pedro I, km 136, Pq. das Universidades, Campinas, SP, 13086-900, Brazil aut NATIONALLICENCE 700 1- Steffen Rafael A. Pontifícia Universidade Católica de Campinas, Faculdade de Química, Campus I, Rod. D. Pedro I, km 136, Pq. das Universidades, Campinas, SP, 13086-900, Brazil aut NATIONALLICENCE 700 1- Shul'pin Georgiy B. Semenov Institute of Chemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow 119991, Russia aut NATIONALLICENCE 773 0- Reaction Kinetics and Catalysis Letters Kluwer Academic Publishers 88/1(2006-06-01), 165-173 0133-1736 88:1<165 2006 88 11144 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer