caa a22 4500 467904170 CHVBK 20180406152828.0 cr unu---uuuuu 170328e20061001xx s 000 0 eng 10.1007/s10661-005-9139-8 doi (NATIONALLICENCE)springer-10.1007/s10661-005-9139-8 Determination of Steroid Estrogens in Wastewater Treatment Plant of A Controceptives Producing Factory [Elektronische Daten] [C. Cui, S. Ji, H. Ren] Steroid estrogens such as estrone (E1), 17β-estradiol (E2), estriol (E3), and 17α-ethynylestradiol (EE2) have been suspected to be the main contaminants, which can affect the endocrine system of animals. Many authors have investigated these chemicals in the domestic wastewater treatment plants (WTP). However, wastewater from industries producing steroid contraceptives has not got ample attention. From the environmental point of view, the four steroids are very significant because even very low concentrations (ng/L) can cause reproductive disturbances in human, livestock and wildlife. The main purpose of the present investigation was to develop an analytical method for the determination of the four steroid estrogens present in WTP of a pharmacy factory, mainly producing contraceptive medicine in Beijing, China. Analysis was performed by solid-phase extraction (SPE) system and liquid chromatography combined with tandem mass spectrometry (LC/MS/MS). The average recoveries from effluent samples ranged from 88% to 103% and the precision of the method ranged from 9% to 4%. Based on 0.5-L wastewater samples, the limit of quantification (LOQ) was determined at 0.7 ng/L for E1, 0.8 for E2, 0.9 ng/L for E3, and 0.5 ng/L for EE2 in influent, and 1.0 ng/L for E2 and EE2, and 2.0 ng/L for E1 and E3 in effluent. In the influent samples, average concentrations of 80, 85, 73 and 155 ng/L were determined for E1, E2, E3 and EE2, respectively, showing that they were removed in this WTP to the extent of 79, 73, 85 and 67%, respectively. Springer Science+Business Media, Inc., 2006 E1 nationallicence E2 nationallicence E3 nationallicence EE2 nationallicence LC/MS/MS nationallicence LOQ nationallicence SPE nationallicence steroid estrogens nationallicence WTP nationallicence Cui C. College of Environment and Energy Engineering, Beijing University of Technology, 100022, Beijing, China aut Ji S. College of Environment and Energy Engineering, Beijing University of Technology, 100022, Beijing, China aut Ren H. College of Environment and Energy Engineering, Beijing University of Technology, 100022, Beijing, China aut Environmental Monitoring and Assessment Springer Netherlands 121/1-3(2006-10-01), 409-419 0167-6369 121:1-3<409 2006 121 10661 https://doi.org/10.1007/s10661-005-9139-8 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10661-005-9139-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cui C. College of Environment and Energy Engineering, Beijing University of Technology, 100022, Beijing, China aut NATIONALLICENCE 700 1- Ji S. College of Environment and Energy Engineering, Beijing University of Technology, 100022, Beijing, China aut NATIONALLICENCE 700 1- Ren H. College of Environment and Energy Engineering, Beijing University of Technology, 100022, Beijing, China aut NATIONALLICENCE 773 0- Environmental Monitoring and Assessment Springer Netherlands 121/1-3(2006-10-01), 409-419 0167-6369 121:1-3<409 2006 121 10661 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer