caa a22 4500 46790555X CHVBK 20180406152833.0 cr unu---uuuuu 170328e20060901xx s 000 0 eng 10.1007/s10735-006-9042-9 doi (NATIONALLICENCE)springer-10.1007/s10735-006-9042-9 The Polycomb group protein Enhancer of Zeste 2: its links to DNA repair and breast cancer [Elektronische Daten] [Michael Zeidler, Celina Kleer] The Polycomb group protein EZH2 is a transcriptional repressor involved in controlling cellular memory and has been linked to tumorigenesis in multiple organs. In this review we summarize the current knowledge on the function of EZH2 in cancer, with special focus on breast cancer, and propose a link between EZH2, the homologous recombination pathway of DNA repair, and breast tumorigenesis. Springer Science+Business Media B.V., 2006 EZH2 nationallicence Breast cancer nationallicence DNA repair nationallicence Homologous recombination nationallicence Biomarker nationallicence Prognosis nationallicence Polycomb nationallicence RAD51 nationallicence RAD51 paralogs nationallicence RAD51L1 nationallicence Zeidler Michael Department of Pathology and Comprehensive Cancer Center, University of Michigan, 3510C MSRB1, 1150 W. Medical Center Dr., 48109, Ann Arbor, MI, USA aut Kleer Celina Department of Pathology and Comprehensive Cancer Center, University of Michigan, 3510C MSRB1, 1150 W. Medical Center Dr., 48109, Ann Arbor, MI, USA aut Journal of Molecular Histology Kluwer Academic Publishers 37/5-7(2006-09-01), 219-223 1567-2379 37:5-7<219 2006 37 10735 https://doi.org/10.1007/s10735-006-9042-9 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10735-006-9042-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zeidler Michael Department of Pathology and Comprehensive Cancer Center, University of Michigan, 3510C MSRB1, 1150 W. Medical Center Dr., 48109, Ann Arbor, MI, USA aut NATIONALLICENCE 700 1- Kleer Celina Department of Pathology and Comprehensive Cancer Center, University of Michigan, 3510C MSRB1, 1150 W. Medical Center Dr., 48109, Ann Arbor, MI, USA aut NATIONALLICENCE 773 0- Journal of Molecular Histology Kluwer Academic Publishers 37/5-7(2006-09-01), 219-223 1567-2379 37:5-7<219 2006 37 10735 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer