caa a22 4500 467905622 CHVBK 20180406152833.0 cr unu---uuuuu 170328e20060901xx s 000 0 eng 10.1007/s10735-006-9047-4 doi (NATIONALLICENCE)springer-10.1007/s10735-006-9047-4 Chromatin remodeling and repair of DNA double-strand breaks [Elektronische Daten] [Lai-Yee Wong, Judith Recht, Brehon Laurent] Eukaryotic cells have developed conserved mechanisms to efficiently sense and repair DNA damage that results from constant chromosomal lesions. DNA repair has to proceed in the context of chromatin, and both histone-modifiers and ATP-dependent chromatin remodelers have been implicated in this process. Here, we review the current understanding and new hypotheses on how different chromatin-modifying activities function in DNA repair in yeast and metazoan cells. Springer Science+Business Media B.V., 2006 Chromatin remodeling nationallicence RSC nationallicence Double-strand break nationallicence DNA repair nationallicence SWI/SNF nationallicence Histone modifications nationallicence Nucleosome nationallicence Cohesin nationallicence Cancer nationallicence Wong Lai-Yee Department of oncological sciences, Mount Sinai School of Medicine, Icahn Medical Institute, 1425 Madison Ave., 10029, New York, NY, USA aut Recht Judith Department of oncological sciences, Mount Sinai School of Medicine, Icahn Medical Institute, 1425 Madison Ave., 10029, New York, NY, USA aut Laurent Brehon Department of oncological sciences, Mount Sinai School of Medicine, Icahn Medical Institute, 1425 Madison Ave., 10029, New York, NY, USA aut Journal of Molecular Histology Kluwer Academic Publishers 37/5-7(2006-09-01), 261-269 1567-2379 37:5-7<261 2006 37 10735 https://doi.org/10.1007/s10735-006-9047-4 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10735-006-9047-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wong Lai-Yee Department of oncological sciences, Mount Sinai School of Medicine, Icahn Medical Institute, 1425 Madison Ave., 10029, New York, NY, USA aut NATIONALLICENCE 700 1- Recht Judith Department of oncological sciences, Mount Sinai School of Medicine, Icahn Medical Institute, 1425 Madison Ave., 10029, New York, NY, USA aut NATIONALLICENCE 700 1- Laurent Brehon Department of oncological sciences, Mount Sinai School of Medicine, Icahn Medical Institute, 1425 Madison Ave., 10029, New York, NY, USA aut NATIONALLICENCE 773 0- Journal of Molecular Histology Kluwer Academic Publishers 37/5-7(2006-09-01), 261-269 1567-2379 37:5-7<261 2006 37 10735 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer