caa a22 4500 467905681 CHVBK 20180406152833.0 cr unu---uuuuu 170328e20061101xx s 000 0 eng 10.1007/s10735-006-9061-6 doi (NATIONALLICENCE)springer-10.1007/s10735-006-9061-6 Neuronal nitric oxide synthase immunopositive neurons in cat vestibular complex: a light and electron microscopic study [Elektronische Daten] [V. Papantchev, A. Paloff, D. Hinova-Palova, S. Hristov, D. Todorova, W. Ovtscharoff] Nitric oxide is a unique neurotransmitter, which participates in many physiological and pathological processes in the organism. Nevertheless, there are little data about the neuronal nitric oxide synthase immunoreactivity (nNOS-ir) in the vestibular complex of a cat. In this respect, the aims of this study were to: (1) demonstrate nNOS-ir in the neurons and fibers, from all major and accessory vestibular nuclei; (2) describe their light microscopic morphology and distribution; (3) investigate and analyze the ultrastructure of the NOS I-immunopositive neurons, fibers, and synaptic boutons. For demonstration of the nNOS-ir, the peroxidase-antiperoxidase-diaminobenzidin method was applied. Immunopositive for nNOS neurons and fibers were present in all major and accessory vestibular nuclei. On the light microscope level, the immunopositive neurons were different in shape and size. According to the latter, they were divided into four groups—small (with diameter less than 15μm), medium-sized (with diameter from 15 to 30μm), large type I (with diameter from 30 to 40μm), and large type II (with diameter greater than 40μm). On the electron microscope level, the immunoproduct was observed in neurons, dendrites, and terminal boutons. According to the ultrastructural features, the neurons were divided into three groups—small (with diameter less than 15μm), medium-sized (with diameter from 15 to 30μm), and large (with diameter greater than 30μm). At least two types of nNOS-ir synaptic boutons were easily distinguished. As a conclusion, we hope that this study will contribute to a better understanding of the functioning of the vestibular complex in cat and that some of the data presented could be extrapolated to other mammals, including human. Springer Science+Business Media, Inc., 2006 Cat nationallicence Vestibular complex nationallicence NOS nationallicence Light microscopy nationallicence Ultrastructure nationallicence VNC : Vestibular nuclear complex nationallicence MVN : Medial vestibular nucleus nationallicence IVN : Inferior vestibular nucleus nationallicence LVN : Lateral vestibular nucleus nationallicence SVN : Superior vestibular nucleus nationallicence fg : f group nationallicence lg : l group nationallicence Xg : X group nationallicence Yg : Y group nationallicence Zg : Z group nationallicence Cn : Cajal's nucleus nationallicence Papantchev V. Department of Anatomy and Histology, Medical University, 1431, Sofia, Bulgaria aut Paloff A. Department of Anatomy and Histology, Medical University, 1431, Sofia, Bulgaria aut Hinova-Palova D. Department of Anatomy and Histology, Medical University, 1431, Sofia, Bulgaria aut Hristov S. Department of Forensic Medicine, Medical University, 1431, Sofia, Bulgaria aut Todorova D. Department of General, Experimental and Genetic Psychology, University of Sofia, 1504, Sofia, Bulgaria aut Ovtscharoff W. Department of Anatomy and Histology, Medical University, 1431, Sofia, Bulgaria aut Journal of Molecular Histology Kluwer Academic Publishers 37/8-9(2006-11-01), 343-352 1567-2379 37:8-9<343 2006 37 10735 https://doi.org/10.1007/s10735-006-9061-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10735-006-9061-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Papantchev V. Department of Anatomy and Histology, Medical University, 1431, Sofia, Bulgaria aut NATIONALLICENCE 700 1- Paloff A. Department of Anatomy and Histology, Medical University, 1431, Sofia, Bulgaria aut NATIONALLICENCE 700 1- Hinova-Palova D. Department of Anatomy and Histology, Medical University, 1431, Sofia, Bulgaria aut NATIONALLICENCE 700 1- Hristov S. Department of Forensic Medicine, Medical University, 1431, Sofia, Bulgaria aut NATIONALLICENCE 700 1- Todorova D. Department of General, Experimental and Genetic Psychology, University of Sofia, 1504, Sofia, Bulgaria aut NATIONALLICENCE 700 1- Ovtscharoff W. Department of Anatomy and Histology, Medical University, 1431, Sofia, Bulgaria aut NATIONALLICENCE 773 0- Journal of Molecular Histology Kluwer Academic Publishers 37/8-9(2006-11-01), 343-352 1567-2379 37:8-9<343 2006 37 10735 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer