caa a22 4500 467907463 CHVBK 20180406152838.0 cr unu---uuuuu 170328e20060601xx s 000 0 eng 10.1007/s00251-006-0104-7 doi (NATIONALLICENCE)springer-10.1007/s00251-006-0104-7 IL-18 gene promoter polymorphism is involved in HIV-1 infection in a Brazilian pediatric population [Elektronische Daten] [Ludovica Segat, Daiana Bevilacqua, Michele Boniotto, Luiz Arraes, Paulo de Souza, Josè de Lima Filho, Sergio Crovella] In our study, we identified a polymorphism (C-607A) in the promoter region of the IL-18 gene that shows different frequencies between human immunodeficiency virus (HIV)-1-infected children and healthy controls in a pediatric Brazilian population. The presence of the −607 C allele correlates to HIV-1 infection and confers an increased risk of infection in subjects carrying the single nucleotide polymorphism. Springer-Verlag, 2006 IL-18 nationallicence HIV-1 infection nationallicence Brazilian children nationallicence Promoter polymorphism nationallicence Single-tube allele-specific PCR nationallicence Segat Ludovica Department of Reproductive and Developmental Sciences, University of Trieste, Via dell'Istria 65/1, 34137, Trieste, Italy aut Bevilacqua Daiana Department of Reproductive and Developmental Sciences, University of Trieste, Via dell'Istria 65/1, 34137, Trieste, Italy aut Boniotto Michele Genetic Service, Children's Hospital Burlo Garofolo, Trieste, Italy aut Arraes Luiz Instituto Materno Infantil do Pernambuco, Recife, Brazil aut de Souza Paulo Laboratorio de Imunopatologia Keizo Azami, Universitade Federal do Pernambuco, Recife, Brazil aut de Lima Filho Josè Laboratorio de Imunopatologia Keizo Azami, Universitade Federal do Pernambuco, Recife, Brazil aut Crovella Sergio Department of Reproductive and Developmental Sciences, University of Trieste, Via dell'Istria 65/1, 34137, Trieste, Italy aut Immunogenetics Springer-Verlag 58/5-6(2006-06-01), 471-473 0093-7711 58:5-6<471 2006 58 251 https://doi.org/10.1007/s00251-006-0104-7 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00251-006-0104-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Segat Ludovica Department of Reproductive and Developmental Sciences, University of Trieste, Via dell'Istria 65/1, 34137, Trieste, Italy aut NATIONALLICENCE 700 1- Bevilacqua Daiana Department of Reproductive and Developmental Sciences, University of Trieste, Via dell'Istria 65/1, 34137, Trieste, Italy aut NATIONALLICENCE 700 1- Boniotto Michele Genetic Service, Children's Hospital Burlo Garofolo, Trieste, Italy aut NATIONALLICENCE 700 1- Arraes Luiz Instituto Materno Infantil do Pernambuco, Recife, Brazil aut NATIONALLICENCE 700 1- de Souza Paulo Laboratorio de Imunopatologia Keizo Azami, Universitade Federal do Pernambuco, Recife, Brazil aut NATIONALLICENCE 700 1- de Lima Filho Josè Laboratorio de Imunopatologia Keizo Azami, Universitade Federal do Pernambuco, Recife, Brazil aut NATIONALLICENCE 700 1- Crovella Sergio Department of Reproductive and Developmental Sciences, University of Trieste, Via dell'Istria 65/1, 34137, Trieste, Italy aut NATIONALLICENCE 773 0- Immunogenetics Springer-Verlag 58/5-6(2006-06-01), 471-473 0093-7711 58:5-6<471 2006 58 251 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer