caa a22 4500 467907730 CHVBK 20180406152839.0 cr unu---uuuuu 170328e20061101xx s 000 0 eng 10.1007/s00251-006-0149-7 doi (NATIONALLICENCE)springer-10.1007/s00251-006-0149-7 Two new Ig VH gene families in Oncorhynchus mykiss [Elektronische Daten] [Gwynne Brown, Ilsa Kaattari, Stephen Kaattari] Genes encoding the immunoglobulin heavy-chain variable region (Ig VH) in rainbow trout (Oncorhynchus mykiss) have been grouped into 11 families. While obtaining a baseline assessment of the various gene families utilized by trout in the production of secreted antibody, we discovered two new families. These proposed Ig VH families, Families XII and XIII, were rarely observed; only two VH sequence types were detected for each new family, suggesting that they may not be commonly used in response to antigens, or that the captive environment may not lead to typical exposures seen in the wild. Additionally, unlike preceding studies, we found at least one representative gene sequence for each of the 11 reported Ig VH gene families, possibly indicating that the repertoire of trout Ig VH gene families may be more universal among different stocks than previously realized. Springer-Verlag, 2006 Oncorhynchus mykiss nationallicence Immunoglobulin heavy-chain variable region nationallicence Ig VH gene nationallicence Brown Gwynne Virginia Institute of Marine Science, P.O. Box 1346, 23062, Gloucester Point, VA, USA aut Kaattari Ilsa Virginia Institute of Marine Science, P.O. Box 1346, 23062, Gloucester Point, VA, USA aut Kaattari Stephen Virginia Institute of Marine Science, P.O. Box 1346, 23062, Gloucester Point, VA, USA aut Immunogenetics Springer-Verlag 58/11(2006-11-01), 933-936 0093-7711 58:11<933 2006 58 251 https://doi.org/10.1007/s00251-006-0149-7 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00251-006-0149-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Brown Gwynne Virginia Institute of Marine Science, P.O. Box 1346, 23062, Gloucester Point, VA, USA aut NATIONALLICENCE 700 1- Kaattari Ilsa Virginia Institute of Marine Science, P.O. Box 1346, 23062, Gloucester Point, VA, USA aut NATIONALLICENCE 700 1- Kaattari Stephen Virginia Institute of Marine Science, P.O. Box 1346, 23062, Gloucester Point, VA, USA aut NATIONALLICENCE 773 0- Immunogenetics Springer-Verlag 58/11(2006-11-01), 933-936 0093-7711 58:11<933 2006 58 251 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer