caa a22 4500 467919178 CHVBK 20180406152911.0 cr unu---uuuuu 170328e20060601xx s 000 0 eng 10.1007/s00706-006-0467-3 doi (NATIONALLICENCE)springer-10.1007/s00706-006-0467-3 Synthesis, Characterization, and Biological Activity of Amino Acid Derivatives of the Heteropolytungstophosphoric Acid [Elektronische Daten] [Vesna Kuntić, Maja Stanojević, Ivanka Holclajtner-Antunović, Snežana Uskoković-Marković, Ubavka Mioč, Marija Todorović, Tanja Jovanović, Vladana Vukojević] Summary.: Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2. Springer-Verlag, 2006 Keywords. Heteropoly compounds nationallicence Amino acids nationallicence IR spectroscopy nationallicence Cellular toxicity nationallicence Antiviral activity nationallicence Kuntić Vesna Department of Physical Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia and Montenegro aut Stanojević Maja Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia and Montenegro aut Holclajtner-Antunović Ivanka Faculty of Physical Chemistry, University of Belgrade, Belgrade, Serbia and Montenegro aut Uskoković-Marković Snežana Department of Analytical Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia and Montenegro aut Mioč Ubavka Faculty of Physical Chemistry, University of Belgrade, Belgrade, Serbia and Montenegro aut Todorović Marija Faculty of Chemistry, University of Belgrade, Belgrade, Serbia and Montenegro aut Jovanović Tanja Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia and Montenegro aut Vukojević Vladana Karolinska Institutet, Center for Molecular Medicine, Stockholm, Sweden aut Monatshefte für Chemie / Chemical Monthly Springer-Verlag 137/6(2006-06-01), 803-810 0026-9247 137:6<803 2006 137 706 https://doi.org/10.1007/s00706-006-0467-3 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00706-006-0467-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kuntić Vesna Department of Physical Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia and Montenegro aut NATIONALLICENCE 700 1- Stanojević Maja Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia and Montenegro aut NATIONALLICENCE 700 1- Holclajtner-Antunović Ivanka Faculty of Physical Chemistry, University of Belgrade, Belgrade, Serbia and Montenegro aut NATIONALLICENCE 700 1- Uskoković-Marković Snežana Department of Analytical Chemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia and Montenegro aut NATIONALLICENCE 700 1- Mioč Ubavka Faculty of Physical Chemistry, University of Belgrade, Belgrade, Serbia and Montenegro aut NATIONALLICENCE 700 1- Todorović Marija Faculty of Chemistry, University of Belgrade, Belgrade, Serbia and Montenegro aut NATIONALLICENCE 700 1- Jovanović Tanja Institute of Microbiology and Immunology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia and Montenegro aut NATIONALLICENCE 700 1- Vukojević Vladana Karolinska Institutet, Center for Molecular Medicine, Stockholm, Sweden aut NATIONALLICENCE 773 0- Monatshefte für Chemie / Chemical Monthly Springer-Verlag 137/6(2006-06-01), 803-810 0026-9247 137:6<803 2006 137 706 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer