caa a22 4500 467919410 CHVBK 20180406152912.0 cr unu---uuuuu 170328e20060901xx s 000 0 eng 10.1007/s00706-006-0520-2 doi (NATIONALLICENCE)springer-10.1007/s00706-006-0520-2 Rapid and Simple Method for Simultaneous Determination of Escin and Diethylamine Salicylate in Pharmaceutical Preparations by Partial Least-Squares Multivariate Calibration [Elektronische Daten] [Özlem Aksu Dönmez, Abdürrezzak Bozdoğan, Gönül Kunt] Summary.: A partial least-squares calibration (PLS) method has been developed for simultaneous quantitative determination of escin (ES) and diethylamine salicylate (DAS) in pharmaceutical preparations. The resolution of these mixtures has been accomplished without prior separation or derivatisation, by using partial least-squares (PLS-2) regression analysis of electronic absorption spectral data. The experimental calibration matrix was constructed with 9 samples. The concentration ranges considered were 10, 20, 30 (ES) and 40, 50, 60 (DAS) μg cm−3. The absorbances were recorded between 200 and 325 nm every 5 nm. Proposed method was compared with conventional spectrophotometric method. The results show that PLS-2 is a simple, rapid, and accurate method applied to the determination of these compounds in pharmaceuticals. Springer-Verlag, 2006 Keywords. Spectrophotometry nationallicence Multivariate calibration nationallicence Escin nationallicence Diethylamine salicylate nationallicence Dönmez Özlem Aksu Chemistry Department, Yildiz Technical University, Davutpasa, Turkey, İstanbul aut Bozdoğan Abdürrezzak Chemistry Department, Yildiz Technical University, Davutpasa, Turkey, İstanbul aut Kunt Gönül Chemistry Department, Yildiz Technical University, Davutpasa, Turkey, İstanbul aut Monatshefte für Chemie / Chemical Monthly Springer-Verlag 137/9(2006-09-01), 1163-1168 0026-9247 137:9<1163 2006 137 706 https://doi.org/10.1007/s00706-006-0520-2 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00706-006-0520-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dönmez Özlem Aksu Chemistry Department, Yildiz Technical University, Davutpasa, Turkey, İstanbul aut NATIONALLICENCE 700 1- Bozdoğan Abdürrezzak Chemistry Department, Yildiz Technical University, Davutpasa, Turkey, İstanbul aut NATIONALLICENCE 700 1- Kunt Gönül Chemistry Department, Yildiz Technical University, Davutpasa, Turkey, İstanbul aut NATIONALLICENCE 773 0- Monatshefte für Chemie / Chemical Monthly Springer-Verlag 137/9(2006-09-01), 1163-1168 0026-9247 137:9<1163 2006 137 706 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer