caa a22 4500 467921741 CHVBK 20180406152918.0 cr unu---uuuuu 170328e20060201xx s 000 0 ger 10.1007/s10309-006-0187-z doi (NATIONALLICENCE)springer-10.1007/s10309-006-0187-z Hormonelle Zusatztherapie katamenialer Anfälle [Elektronische Daten] [Hanni Jadidzadeh, Jürgen Bauer] Hormonal therapy of catamenial seizures In women with epilepsy, seizure frequency may be increased during distinct phases of the menstrual cycle (catamenial seizures). During ovulatory cycles, catamenial seizures often occur during the days of menstruation (premenstrual decline of progesterone). In cycles with insufficient luteal phase seizure exacerbation may occur during the second half of the cycle (lack of progesterone). We report on six women with catamenial seizures during ovulatory cycles treated with a GnRH analogue (Leuprorelin). Frequency of complex partial seizures decreased in four patients (mean 68%). Following hormonal treatment, seizure frequency remained decreased in most of the patients (however antiepileptic drugs were changed in some of the women). Seizure exacerbation (plus 11%) after hormonal therapy was observed in one woman. Three women discontinued hormonal treatment because of side effects (bone dimineralization, headache). Steinkopff-Verlag, 2006 Epilepsy nationallicence intractability nationallicence GnRH analogues nationallicence Epilepsie nationallicence Pharmakoresistenz nationallicence GnRH-Analogon nationallicence Jadidzadeh Hanni Universitätsklinikum Bonn, Klinik für Epileptologie, Sigmund-Freud-Str. 25, 53105, Bonn aut Bauer Jürgen Universitätsklinikum Bonn, Klinik für Epileptologie, Sigmund-Freud-Str. 25, 53105, Bonn aut Zeitschrift für Epileptologie Steinkopff-Verlag 19/1(2006-02-01), 28-33 1617-6782 19:1<28 2006 19 10309 https://doi.org/10.1007/s10309-006-0187-z text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10309-006-0187-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jadidzadeh Hanni Universitätsklinikum Bonn, Klinik für Epileptologie, Sigmund-Freud-Str. 25, 53105, Bonn aut NATIONALLICENCE 700 1- Bauer Jürgen Universitätsklinikum Bonn, Klinik für Epileptologie, Sigmund-Freud-Str. 25, 53105, Bonn aut NATIONALLICENCE 773 0- Zeitschrift für Epileptologie Steinkopff-Verlag 19/1(2006-02-01), 28-33 1617-6782 19:1<28 2006 19 10309 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer