caa a22 4500 46792189X CHVBK 20180406152919.0 cr unu---uuuuu 170328e20060801xx s 000 0 ger 10.1007/s10309-006-0214-0 doi (NATIONALLICENCE)springer-10.1007/s10309-006-0214-0 Mayer Thomas Kleinwachau, Sächsisches Epilepsiezentrum Radeberg, Wachauer Straße 30, 01454, Radeberg, Germany aut Der Einfluss von Oxcarbazepin auf Hormone [Elektronische Daten] [Thomas Mayer] The influence of oxcarbacepine on hormones Abstract : The literature was analysed with different databases to find relations between oxcarbazepine (OXC) und the hormone system. 46 papers between 1989 and 2005 were screened and investigated. The following facts were found: There is a dose-related influence of OXC on the Cytochrome P450 System of the liver (CYP 3A4) and also an effect on the clearance of ovulation suppressing medication. Also there is a dose-dependent effect of OXC on testosterone and sex hormonebinding globulin. Otherwise we could not find any influence of OXC on secretion of antidiuretic hormone, on the lipid metabolism, on growth and body weight. It is unclear, if there are effects of OXC on thyreoid hormones, sexual mutation and reproductive functions. Steinkopff-Verlag, 2006 Oxcarbacepine nationallicence hormone nationallicence metabolism nationallicence enzyminduction nationallicence sexual maturation nationallicence reproductive functions nationallicence Oxcarbazepin nationallicence Hormone nationallicence Stoffwechsel nationallicence Enzyminduktion nationallicence sexuelle Reifung nationallicence reproduktive Funktion nationallicence Zeitschrift für Epileptologie Steinkopff-Verlag 19/3(2006-08-01), 212-219 1617-6782 19:3<212 2006 19 10309 https://doi.org/10.1007/s10309-006-0214-0 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10309-006-0214-0 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Mayer Thomas Kleinwachau, Sächsisches Epilepsiezentrum Radeberg, Wachauer Straße 30, 01454, Radeberg, Germany aut NATIONALLICENCE 773 0- Zeitschrift für Epileptologie Steinkopff-Verlag 19/3(2006-08-01), 212-219 1617-6782 19:3<212 2006 19 10309 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer