caa a22 4500 467933383 CHVBK 20180406152949.0 cr unu---uuuuu 170328e20060801xx s 000 0 eng 10.1007/s10545-006-0377-x doi (NATIONALLICENCE)springer-10.1007/s10545-006-0377-x Iliopsoas haematoma in Gaucher disease [Elektronische Daten] [Aleksandar Lešić, Nada Suvajdzic, Ivo Elezovic, Marko Bumbasirevic, Irith Hadas-Halpern, Deborah Elstein, Ari Zimran] Summary: Extrapelvis or retroperitoneal haemorrhage has long been appreciated as having many causes and considerable variability in subsequent morbidity; however, to date only two cases have been reported in patients with Gaucher disease, the most common lysosomal storage disorder. It had been our assumption that these cases were unique and a consequence of severe disease in patients who had not been treated with enzyme (or other disease-specific) therapy. Herein we present three more cases (as well as our first patient), which allow one to make some generalizations. Ultrasound was used in one centre and computed tomography in the second centre to make the definitive diagnosis. The trigger for the bleeding in all cases was muscle strain after activity. All patients were young with massive hepatosplenomegaly, anaemia, thrombocytopenia, and bone pain with skeletal involvement; the last was the most obvious commonality among these patients. Differential diagnosis is complicated by exquisite groin pain that is common to both Gaucher disease and extrapelvis haemorrhage, but not necessarily. SSIEM and Springer, 2006 Lešić Aleksandar Institute for Orthopaedic Surgery and Traumatology, CCS, Belgrade, Serbia aut Suvajdzic Nada Institute for Haematology, CCS, Belgrade, Serbia aut Elezovic Ivo Institute for Haematology, CCS, Belgrade, Serbia aut Bumbasirevic Marko Institute for Orthopaedic Surgery and Traumatology, CCS, Belgrade, Serbia aut Hadas-Halpern Irith Department of Diagnostic Radiology, Shaare Zedek Medical Center, Jerusalem, Israel aut Elstein Deborah Gaucher Clinic, Shaare Zedek Medical Center, POB 3235, 91031, Jerusalem, Israel aut Zimran Ari Gaucher Clinic, Shaare Zedek Medical Center, POB 3235, 91031, Jerusalem, Israel aut Journal of Inherited Metabolic Disease Kluwer Academic Publishers 29/4(2006-08-01), 593-593 0141-8955 29:4<593 2006 29 10545 https://doi.org/10.1007/s10545-006-0377-x text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10545-006-0377-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lešić Aleksandar Institute for Orthopaedic Surgery and Traumatology, CCS, Belgrade, Serbia aut NATIONALLICENCE 700 1- Suvajdzic Nada Institute for Haematology, CCS, Belgrade, Serbia aut NATIONALLICENCE 700 1- Elezovic Ivo Institute for Haematology, CCS, Belgrade, Serbia aut NATIONALLICENCE 700 1- Bumbasirevic Marko Institute for Orthopaedic Surgery and Traumatology, CCS, Belgrade, Serbia aut NATIONALLICENCE 700 1- Hadas-Halpern Irith Department of Diagnostic Radiology, Shaare Zedek Medical Center, Jerusalem, Israel aut NATIONALLICENCE 700 1- Elstein Deborah Gaucher Clinic, Shaare Zedek Medical Center, POB 3235, 91031, Jerusalem, Israel aut NATIONALLICENCE 700 1- Zimran Ari Gaucher Clinic, Shaare Zedek Medical Center, POB 3235, 91031, Jerusalem, Israel aut NATIONALLICENCE 773 0- Journal of Inherited Metabolic Disease Kluwer Academic Publishers 29/4(2006-08-01), 593-593 0141-8955 29:4<593 2006 29 10545 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer