caa a22 4500 467935394 CHVBK 20180406152955.0 cr unu---uuuuu 170328e20060501xx s 000 0 eng 10.1007/s10729-006-7662-y doi (NATIONALLICENCE)springer-10.1007/s10729-006-7662-y Saraniti Brett Economics and Quantitative Methods, Hawaii Pacific University, 96813, Honolulu, USA aut Optimal pooled testing [Elektronische Daten] [Brett Saraniti] This paper first characterizes three pooled testing techniques for generic testing conditions. It then applies these methods to demonstrate potential costs savings for universal HIV screening in the United Stated and Thailand. The success of these techniques in general is shown to be dependent on the prevalence as well as the disparity in prevalence between high and low risk groups. Further limitations on effectiveness include the potential impact of dilution on sensitivity. This and other limitations are addressed in the second section which focuses on applications of the techniques. Cost reductions are demonstrated to be feasible at prevalence of up to 30% and increasing dramatically at lower rates. Applying optimal pooled testing to universal HIV screening would result in an annual savings of over $1.4 billion in the United States and over $130 million in Thailand. Recent calls for universal HIV testing are based on the cost effectiveness of routine screening. These assessments may substantially overstate the cost of routine screening which strengthens the argument for universal screening. Springer Science + Business Media, Inc., 2006 Pooled testing nationallicence HIV screening nationallicence Cost reduction nationallicence Health Care Management Science Kluwer Academic Publishers 9/2(2006-05-01), 143-149 1386-9620 9:2<143 2006 9 10729 https://doi.org/10.1007/s10729-006-7662-y text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s10729-006-7662-y text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Saraniti Brett Economics and Quantitative Methods, Hawaii Pacific University, 96813, Honolulu, USA aut NATIONALLICENCE 773 0- Health Care Management Science Kluwer Academic Publishers 9/2(2006-05-01), 143-149 1386-9620 9:2<143 2006 9 10729 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer