caa a22 4500 467939934 CHVBK 20180406153009.0 cr unu---uuuuu 170328e20060901xx s 000 0 eng 10.1007/s00421-006-0217-6 doi (NATIONALLICENCE)springer-10.1007/s00421-006-0217-6 Motion sickness increases the risk of accidental hypothermia [Elektronische Daten] [Gerard Nobel, Ola Eiken, Arne Tribukait, Roger Kölegård, Igor Mekjavic] Motion sickness (MS) has been found to increase body-core cooling during immersion in 28°C water, an effect ascribed to attenuation of the cold-induced peripheral vasoconstriction (Mekjavic et al. in J Physiol 535(2):619-623, 2001). The present study tested the hypothesis that a more profound cold stimulus would override the MS effect on peripheral vasoconstriction and hence on the core cooling rate. Eleven healthy subjects underwent two separate head-out immersions in 15°C water. In the control trial (CN), subjects were immersed after baseline measurements. In the MS-trial, subjects were rendered motion sick prior to immersion, by using a rotating chair in combination with a regimen of standardized head movements. During immersion in the MS-trial, subjects were exposed to an optokinetic stimulus (rotating drum). At 5-min intervals subjects rated their temperature perception, thermal comfort and MS discomfort. During immersion mean skin temperature, rectal temperature, the difference in temperature between the non-immersed right forearm and 3rd finger of the right hand (ΔT ff), oxygen uptake and heart rate were recorded. In the MS-trial, rectal temperature decreased substantially faster (33%, P<0.01). Also, the ΔT ff response, an index of peripheral vasomotor tone, as well as the oxygen uptake, indicative of the shivering response, were significantly attenuated (P<0.01 and P<0.001, respectively) by MS. Thus, MS may predispose individuals to hypothermia by enhancing heat loss and attenuating heat production. This might have significant implications for survival in maritime accidents. Springer-Verlag, 2006 Body temperature regulation nationallicence Vasodilation nationallicence Vasoconstriction nationallicence Shivering nationallicence Nobel Gerard Royal Netherlands Navy, Den Helder, The Netherlands aut Eiken Ola Swedish Defence Research Agency, Berzelius v. 13, Karolinska Institutet, 17177, Stockholm, Sweden aut Tribukait Arne Swedish Defence Research Agency, Berzelius v. 13, Karolinska Institutet, 17177, Stockholm, Sweden aut Kölegård Roger Swedish Defence Research Agency, Berzelius v. 13, Karolinska Institutet, 17177, Stockholm, Sweden aut Mekjavic Igor Department of Automation, Biocybernetics and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia aut European Journal of Applied Physiology Springer-Verlag 98/1(2006-09-01), 48-55 1439-6319 98:1<48 2006 98 421 https://doi.org/10.1007/s00421-006-0217-6 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/s00421-006-0217-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nobel Gerard Royal Netherlands Navy, Den Helder, The Netherlands aut NATIONALLICENCE 700 1- Eiken Ola Swedish Defence Research Agency, Berzelius v. 13, Karolinska Institutet, 17177, Stockholm, Sweden aut NATIONALLICENCE 700 1- Tribukait Arne Swedish Defence Research Agency, Berzelius v. 13, Karolinska Institutet, 17177, Stockholm, Sweden aut NATIONALLICENCE 700 1- Kölegård Roger Swedish Defence Research Agency, Berzelius v. 13, Karolinska Institutet, 17177, Stockholm, Sweden aut NATIONALLICENCE 700 1- Mekjavic Igor Department of Automation, Biocybernetics and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia aut NATIONALLICENCE 773 0- European Journal of Applied Physiology Springer-Verlag 98/1(2006-09-01), 48-55 1439-6319 98:1<48 2006 98 421 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer